One-pot cross-coupling of N-acyl N,O-acetals with α,β-unsaturated compounds

被引：29

作者：

Xiang, Yong-Gang ^{[2
,3
]}

Wang, Xiang-Wu ^{[2
,3
]}

Zheng, Xiao ^{[1
,4
]}

Ruan, Yuan-Ping ^{[2
,3
]}

Huang, Pei-Qiang ^{[2
,3
]}

机构：

[1] Xiamen Univ, Dept Pharmaceut Sci, Coll Med, Xiamen 361005, Fujian, Peoples R China

[2] Xiamen Univ, Coll Chem & Chem Engn, Dept Chem, Xiamen 361005, Fujian, Peoples R China

[3] Xiamen Univ, Coll Chem & Chem Engn, Key Lab Chem Biol Fujian Prov, Xiamen 361005, Fujian, Peoples R China

[4] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synthet Chem Nat Subst, Beijing 100864, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 45期

关键词：

ASYMMETRIC-SYNTHESIS; SAMARIUM DIIODIDE; ACYLIMINIUM IONS; CYCLIZATION REACTIONS; FLEXIBLE APPROACH; GENERATION; CHEMISTRY; AMIDES; ACID; ALKALOIDS;

D O I：

10.1039/b915488d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synergistic action of BF3 center dot OEt2 and SmI2 allowed a series of intermolecular cross-couplings of readily available N-acyl N,O-acetals with alpha,beta-unsaturated compounds to be performed in high yields, which was applied to the stereoselective synthesis of pyrrolizidine alkaloid (+)-xenovenine.

引用

页码：7045 / 7047

页数：3

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