CT and MR imaging of chemotherapy-induced hepatopathy

被引：25

作者：

Vernuccio, Federica ^{[1
,2
,3
]}

Burgio, Marco Dioguardi ^{[3
,4
]}

Barbiera, Filippo ^{[5
]}

Cusma, Silvestro ^{[6
]}

Badalamenti, Giuseppe ^{[7
]}

Midiri, Massimo ^{[8
]}

Vilgrain, Valerie ^{[3
,4
]}

Brancatelli, Giuseppe ^{[8
]}

机构：

[1] Univ Palermo, Univ Hosp Paolo Giaccone, Dipartimento Promoz Salute Maternoinfantile Med I, Via Vespro 129, I-90124 Palermo, Italy

[2] IRCCS Ctr Neurolesi Bonino Pulejo, Contrada Casazza,SS113, I-98124 Messina, Italy

[3] Univ Paris VII, Hop Univ Beaujon, Radiol, Clichy, France

[4] Univ Paris Diderot, Ctr Res Inflammat, INSERM, Lab Imaging Biomarkers,UMR 1149, Paris, France

[5] Presidio Osped Sciacca AG, UO Complessa Radiologia Distretto Ag 2 Sciacca Ri, Azienda Sanit Prov Agrigento, Sciacca, Agrigento, Italy

[6] Oncol Dept, Palermo, Italy

[7] Univ Hosp Paolo Giaccone, Dipartimento Discipline Chirurg Oncol & Stomatol, Palermo, Italy

[8] Univ Palermo, Dipartimento Biomed Neurosci & Diagnost Avanzata, Palermo, Italy

来源：

ABDOMINAL RADIOLOGY | 2019年 / 44卷 / 10期

关键词：

Chemotherapy; Hepatopathy; Computed tomography; Magnetic resonance imaging; Sinusoidal obstruction syndrome; COLORECTAL LIVER METASTASES; NODULAR REGENERATIVE HYPERPLASIA; SINUSOIDAL OBSTRUCTION SYNDROME; OXALIPLATIN-BASED CHEMOTHERAPY; DENSITY FAT FRACTION; HEPATIC STEATOSIS; HEPATECTOMY; RESECTION; INJURY; STEATOHEPATITIS;

D O I：

10.1007/s00261-019-02193-y

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Chemotherapy-induced hepatopathy includes a wide variety of parenchymal and vascular hepatic changes on imaging, including diffuse or focal hepatopathies (i.e. hepatitis, steatosis, fibrosis, pseudocirrhosis, or sinusoidal obstruction). These changes can profoundly alter the hepatic parenchyma on imaging and result in both false negative and false-positive diagnoses of hepatic metastases and lead to errors in patient management strategies. It is therefore important for radiologists to have a comprehensive knowledge of the imaging patterns that may develop following chemotherapy. The purpose of this review is to explore the broad spectrum of hepatic parenchymal and vascular chemotherapy-induced changes on CT and MR imaging.

引用

页码：3312 / 3324

页数：13

共 60 条

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