The role of microglia in Alzheimer's disease: friend or foe?

被引:26
作者
Schenk, DB [1 ]
Yednock, T [1 ]
机构
[1] Elan Pharmaceut, San Francisco, CA 94080 USA
关键词
D O I
10.1016/S0197-4580(02)00034-9
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
引用
收藏
页码:677 / 679
页数:3
相关论文
共 27 条
[1]   A randomized controlled trial of prednisone in Alzheimer's disease [J].
Aisen, PS ;
Davis, KL ;
Berg, JD ;
Schafer, K ;
Campbell, K ;
Thomas, RG ;
Weiner, MF ;
Farlow, MR ;
Sano, M ;
Grundman, M ;
Thal, LJ .
NEUROLOGY, 2000, 54 (03) :588-593
[2]   Inflammation and Alzheimer's disease [J].
Akiyama, H ;
Barger, S ;
Barnum, S ;
Bradt, B ;
Bauer, J ;
Cole, GM ;
Cooper, NR ;
Eikelenboom, P ;
Emmerling, M ;
Fiebich, BL ;
Finch, CE ;
Frautschy, S ;
Griffin, WST ;
Hampel, H ;
Hull, M ;
Landreth, G ;
Lue, LF ;
Mrak, R ;
Mackenzie, IR ;
McGeer, PL ;
O'Banion, MK ;
Pachter, J ;
Pasinetti, G ;
Plata-Salaman, C ;
Rogers, J ;
Rydel, R ;
Shen, Y ;
Streit, W ;
Strohmeyer, R ;
Tooyoma, I ;
Van Muiswinkel, FL ;
Veerhuis, R ;
Walker, D ;
Webster, S ;
Wegrzyniak, B ;
Wenk, G ;
Wyss-Coray, T .
NEUROBIOLOGY OF AGING, 2000, 21 (03) :383-421
[3]  
[Anonymous], 1999, Neurology, V53, P457
[4]   Reduced prevalence of AD in users of NSAIDs and H2 receptor antagonists - The Cache County Study [J].
Anthony, JC ;
Breitner, JCS ;
Zandi, PP ;
Meyer, MR ;
Jurasova, I ;
Norton, MC ;
Stone, SV .
NEUROLOGY, 2000, 54 (11) :2066-2071
[5]   Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease [J].
Bard, F ;
Cannon, C ;
Barbour, R ;
Burke, RL ;
Games, D ;
Grajeda, H ;
Guido, T ;
Hu, K ;
Huang, JP ;
Johnson-Wood, K ;
Khan, K ;
Kholodenko, D ;
Lee, M ;
Lieberburg, I ;
Motter, R ;
Nguyen, M ;
Soriano, F ;
Vasquez, N ;
Weiss, K ;
Welch, B ;
Seubert, P ;
Schenk, D ;
Yednock, T .
NATURE MEDICINE, 2000, 6 (08) :916-919
[6]  
Colton CA, 2000, ANN NY ACAD SCI, V899, P292
[7]   Pharmacologic management of Alzheimer disease part III: Nonsteroidal antiinflammatory drugs - Emerging protective evidence? [J].
Flynn, BL ;
Theesen, KA .
ANNALS OF PHARMACOTHERAPY, 1999, 33 (7-8) :840-849
[8]   Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain [J].
Hoozemans, JJM ;
Rozemuller, AJM ;
Janssen, I ;
De Groot, CJA ;
Veerhuis, R ;
Eikelenboom, P .
ACTA NEUROPATHOLOGICA, 2001, 101 (01) :2-8
[9]   Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease [J].
Janus, C ;
Pearson, J ;
McLaurin, J ;
Mathews, PM ;
Jiang, Y ;
Schmidt, SD ;
Chishti, MA ;
Horne, P ;
Heslin, D ;
French, J ;
Mount, HTJ ;
Nixon, RA ;
Mercken, M ;
Bergeron, C ;
Fraser, PE ;
St George-Hyslop, P ;
Westaway, D .
NATURE, 2000, 408 (6815) :979-982
[10]  
Jellinger KA, 1998, J NEURAL TRANSM-SUPP, P77