Haemagglutinating activity of the lentogenic Newcastle disease virus strain MET95

被引：6

作者：

Murakawa, Y ^{[1
]}

Sakaguchi, M

Soejima, K

Eriguchi, S

Takase, K

Sueyoshi, M

Nagatomo, H

Ito, T

Otsuki, K

机构：

[1] Miyazaki Univ, Fac Agr, Miyazaki 8892155, Japan

[2] Kikuchi Res Ctr, Chemoserotherapeut Res Inst, Kumamoto 8691298, Japan

[3] Kagoshima Univ, Fac Agr, Kagoshima 8900065, Japan

[4] Tottori Univ, Fac Agr, Tottori 6808553, Japan

来源：

AVIAN PATHOLOGY | 2003年 / 32卷 / 01期

关键词：

D O I：

10.1080/0307945021000070705

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Using the rapid glass plate method, the Newcastle disease virus strain MET95 showed much weaker haemagglutination (HA) activity for chicken erythrocytes than 69 other Newcastle disease viruses, including 56 field strains isolated from chickens reared in Japan between 1988 and 2001. Using erythrocytes from other avian species, only the MET95 strain failed to show HA activity for erythrocytes from ducks, geese or pigeons. The haemagglutinin-neuraminidase protein of the MET95 strain was shown to have unique substitutions of isoleucine for thereonine and leucine at amino acide residues 216 and 552. It is suggested that these two substitutions might relate to the unique HA activity of the MET95 strain. This HA activity may be a useful marker for this strain.

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页码：39 / 45

页数：7

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