Methods and issues in studies of CRE

被引:13
作者
Evans, Scott R. [1 ,2 ]
Harris, Anthony D. [3 ]
机构
[1] Harvard Univ, Ctr Biostat AIDS Res, Boston, MA USA
[2] Harvard Univ, Dept Biostat, Boston, MA USA
[3] Univ Maryland, Epidemiol & Publ Hlth, 685 W Baltimore,MSTF 330, College Pk, MD 21201 USA
基金
美国国家卫生研究院;
关键词
carbapenem-resistant Enterobacteriaceae; case-control study; cohort study; competing risk; confounding variable; control group; external control; lead-time bias; randomized trial; RESISTANT STAPHYLOCOCCUS-AUREUS; CONTROL-GROUP SELECTION; LENGTH-OF-STAY; ANTIMICROBIAL RESISTANCE; ANTIBIOTIC-RESISTANCE; RISK-FACTORS; INFECTIONS; COLONIZATION; ORGANISMS; MORTALITY;
D O I
10.1080/21505594.2016.1213473
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging and troublesome group of pathogens. Risk factor studies, outcome studies, and randomized trials are three types of studies conducted to answer different types of questions regarding CRE. These studies pose different types of challenges. We discuss issues in the design and analyses of case-control studies, cohort studies, and randomized trials aimed to address various research questions regarding CRE.
引用
收藏
页码:453 / 459
页数:7
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