Mucoepidermoid Carcinoma of the Parotid as a Secondary Malignancy After Chemotherapy in a Child With Neuroblastoma

被引：9

作者：

Blatt, Julie ^{[1
,2
]}

Zdanski, Carlton ^{[3
]}

Scanga, Lori ^{[4
]}

Rao, Kathleen W. ^{[1
,5
]}

Morris, David E. ^{[6
]}

Shockley, William W. ^{[3
]}

机构：

[1] Univ N Carolina, Sch Med, Dept Pediat, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Sch Med, Div Pediat Hematol Oncol, Chapel Hill, NC 27599 USA

[3] Univ N Carolina, Sch Med, Dept Otolaryngol Head & Neck Surg, Chapel Hill, NC 27599 USA

[4] Univ N Carolina, Sch Med, Dept Surg Pathol, Chapel Hill, NC 27599 USA

[5] Univ N Carolina, Sch Med, Dept Pathol & Genet, Chapel Hill, NC 27599 USA

[6] Univ N Carolina, Sch Med, Dept Radiat Oncol, Chapel Hill, NC 27599 USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2013年 / 35卷 / 05期

关键词：

neuroblastoma; mucoepidermoid carcinoma; secondary malignancy; parotid; ACUTE LYMPHOBLASTIC-LEUKEMIA; CANCER SURVIVOR; TUMORS; GLAND;

D O I：

10.1097/MPH.0b013e3182468c55

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Secondary neoplasms are not reported frequently after neuroblastoma, which until recently was a cancer with limited long-term survival. Although salivary gland tumors in children and adolescents may be idiopathic, they are seen more often after head and neck radiation. We report a child with stage 4 neuroblastoma treated with high-dose multiagent chemotherapy without radiation therapy to his neck who, within 1 year of treatment, developed a low-grade but large and locally aggressive mucoepidermoid carcinoma of his parotid gland further characterized by a t(11;19)(q21;p13.1). Our patient extends the spectrum of secondary neoplasms after neuroblastoma.

引用

页码：399 / 401

页数：3

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