A review of UMAP in population genetics

被引：96

作者：

Diaz-Papkovich, Alex ^{[1
,2
]}

Anderson-Trocme, Luke ^{[2
]}

Gravel, Simon ^{[2
]}

机构：

[1] McGill Univ, Quantitat Life Sci Program, Montreal, PQ, Canada

[2] McGill Univ, Dept Human Genet, Montreal, PQ, Canada

来源：

JOURNAL OF HUMAN GENETICS | 2021年 / 66卷 / 01期

关键词：

DESIGN;

D O I：

10.1038/s10038-020-00851-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Uniform manifold approximation and projection (UMAP) has been rapidly adopted by the population genetics community to study population structure. It has become common in visualizing the ancestral composition of human genetic datasets, as well as searching for unique clusters of data, and for identifying geographic patterns. Here we give an overview of applications of UMAP in population genetics, provide recommendations for best practices, and offer insights on optimal uses for the technique.

引用

页码：85 / 91

页数：7

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