An Overview of Plant Phenolic Compounds and Their Importance in Human Nutrition and Management of Type 2 Diabetes

被引:631
作者
Lin, Derong [1 ]
Xiao, Mengshi [1 ]
Zhao, Jingjing [1 ]
Li, Zhuohao [1 ]
Xing, Baoshan [2 ]
Li, Xindan [1 ]
Kong, Maozhu [1 ]
Li, Liangyu [1 ]
Zhang, Qing [1 ]
Liu, Yaowen [1 ]
Chen, Hong [1 ]
Qin, Wen [1 ]
Wu, Hejun [1 ]
Chen, Saiyan [1 ]
机构
[1] Sichuan Agr Univ, Coll Food Sci, 46 Xinkang Rd, Yaan 625014, Sichuan, Peoples R China
[2] Univ Massachusetts, Stockbridge Sch Agr, Amherst, MA 01003 USA
来源
MOLECULES | 2016年 / 21卷 / 10期
关键词
phenolic compounds; biosynthesis; function; complication; type; 2; diabetes; ALPHA-GLUCOSIDASE; ANTIOXIDANT ACTIVITY; DIETARY POLYPHENOLS; BIOACTIVE COMPOUNDS; OXIDATIVE STRESS; BLOOD-PRESSURE; PHASEOLUS-VULGARIS; DIOSPYROS-KAKI; KEY ENZYMES; GRAPE SEED;
D O I
10.3390/molecules21101374
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this paper, the biosynthesis process of phenolic compounds in plants is summarized, which includes the shikimate, pentose phosphate and phenylpropanoid pathways. Plant phenolic compounds can act as antioxidants, structural polymers (lignin), attractants (flavonoids and carotenoids), UV screens (flavonoids), signal compounds (salicylic acid and flavonoids) and defense response chemicals (tannins and phytoalexins). From a human physiological standpoint, phenolic compounds are vital in defense responses, such as anti-aging, anti-inflammatory, antioxidant and anti-proliferative activities. Therefore, it is beneficial to eat such plant foods that have a high antioxidant compound content, which will cut down the incidence of certain chronic diseases, for instance diabetes, cancers and cardiovascular diseases, through the management of oxidative stress. Furthermore, berries and other fruits with low-amylase and high-glucosidase inhibitory activities could be regarded as candidate food items in the control of the early stages of hyperglycemia associated with type 2 diabetes.
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页数:19
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