Roles of ERCP in the Early Diagnosis of Pancreatic Cancer

被引:32
作者
Hanada, Keiji [1 ]
Minami, Tomoyuki [1 ]
Shimizu, Akinori [1 ]
Fukuhara, Motomitsu [1 ]
Yano, Shigeki [1 ]
Sasaki, Kenji [2 ]
Koda, Masanori [2 ]
Sugiyama, Kayo [2 ]
Yonehara, Shuji [2 ]
Yanagisawa, Akio [3 ]
机构
[1] Onomichi Gen Hosp, Dept Gastroenterol, Onomichi 7228508, Japan
[2] Onomichi Gen Hosp, Dept Pathol, Onomichi 7228508, Japan
[3] Kyoto First Red Cross Hosp, Dept Pathol, Kyoto 6050981, Japan
关键词
pancreatic cancer; ERCP; cytology; SPACE; early diagnosis; CARCINOMA IN-SITU; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; LOW PAPILLARY TYPE; NASOPANCREATIC DRAINAGE; FLAT TYPE; JUICE; PANCREATOGRAPHY;
D O I
10.3390/diagnostics9010030
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
It has been reported that endoscopic retrograde cholangiopancreatography (ERCP) is of value in evaluating precise pancreatograms of the pancreatic duct (PD). Recently, institutions have tended to perform magnetic resonance cholangiopancreatography (MRCP) for the diagnosis of PD due to post-ERCP pancreatitis (PEP). In small pancreatic cancer (PC), including PC in situ (PCIS) which is undetectable on cross sectional images, endoscopic ultrasonography (EUS) and MRCP serve important roles in detecting local irregular stenosis of the PD or small cystic lesions. Subsequently, ERCP and associated serial pancreatic juice aspiration cytologic examination (SPACE) obtained by endoscopic nasopancreatic drainage (ENPD) may be useful in the diagnosis of very early-stage PC. Further prospective multicenter studies are required to establish a standard method of SPACE for the early diagnosis of PC.
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页数:10
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