Anti-tumor efficacy of the 3.19.3 ANG-2 antibody in combination with VEGF inhibitors in tumor xenograft models

被引：0
|
作者：
Brown, Jeff
Cao, Zhu
Reimer, Corinne
Zhou, Qing
Kendrew, Jane
Ryan, Anderson
Jurgensmeier, Juliane
Emery, Steve
Blakey, David
机构：
[1] AstraZeneca, Waltham, MA USA
[2] Abgenix Inc, Fremont, CA USA
[3] AstraZeneca, Macclesfield, Cheshire, England
来源：
CANCER RESEARCH | 2009年 / 69卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
127
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Identification of a human antibody 3.19.3 that inhibits ANG-2 function leading to significant anti-tumor activity in a panel of tumor xenograft models
    Blakey, David
    Emery, Steve
    Zhou, Qing
    Kendrew, Jane
    Cao, Zhu
    Brown, Jeff
    CANCER RESEARCH, 2009, 69
  • [2] Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival
    Kloepper, Jonas
    Riedemann, Lars
    Amoozgar, Zohreh
    Seano, Giorgio
    Susek, Katharina
    Yu, Veronica
    Dalvie, Nisha
    Amelung, Robin L.
    Datta, Meenal
    Song, Jonathan W.
    Askoxylakis, Vasileios
    Taylor, Jennie W.
    Lu-Emerson, Christine
    Batista, Ana
    Kirkpatrick, Nathaniel D.
    Jung, Keehoon
    Snuderl, Matija
    Muzikansky, Alona
    Stubenrauch, Kay G.
    Krieter, Oliver
    Wakimoto, Hiroaki
    Xu, Lei
    Munn, Lance L.
    Duda, Dan G.
    Fukumura, Dai
    Batchelor, Tracy T.
    Jain, Rakesh K.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (16) : 4476 - 4481
  • [3] Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival
    Kloepper, Jonas
    Riedemann, Lars
    Amoozgar, Zohreh
    Seano, Giorgio
    Susek, Katharina H.
    Yu, Veronica
    Dalvie, Nisha
    Amelung, Robin L.
    Datta, Meenal
    Song, Jonathan W.
    Askoxylakis, Vasileios
    Taylor, Jennie W.
    Lu-Emerson, Christine
    Batista, Ana
    Kirkpatrick, Nathaniel D.
    Jung, Keehoon
    Snuderl, Matija
    Muzikansky, Alona
    Stubenrauch, Kay G.
    Krieter, Oliver
    Wakimoto, Hiroaki
    Xu, Lei
    Munn, Lance L.
    Duda, Dan G.
    Fukumura, Dai
    Batchelor, Tracy T.
    Jain, Rakesh K.
    CANCER RESEARCH, 2016, 76
  • [4] Combination of angiogenesis inhibitors increases the anti-tumor efficacy of photodynamic therapy in a human bladder tumor xenograft model
    Bhuvaneswari, Ramaswamy
    Gan, Yik Yuen
    Thong, Patricia S. P.
    Chin, William Wei Lim
    Soo, Khee Chee
    Olivo, Malini
    12TH WORLD CONGRESS OF THE INTERNATIONAL PHOTODYNAMIC ASSOCIATION: PHOTODYNAMIC THERAPY: BACK TO THE FUTURE, 2009, 7380
  • [5] REPROGRAMMING OF THE TUMOR IMMUNE MICROENVIRONMENT BY AN ANG-2/VEGF BISPECIFIC ANTIBODY DELAYS TUMOR GROWTH AND PROLONGS SURVIVAL IN PRECLINICAL GBM MODELS
    Riedemann, Lars
    Kloepper, Jonas
    Amoozgar, Zohreh
    Seano, Giorgio
    Susek, Katharina
    Yu, Veronica
    Dalvie, Nisha
    Amelung, Robin
    Datta, Meenal
    Song, Jonathan W.
    Askoxylakis, Vasileios
    Taylor, Jennie
    Lu-Emerson, Christine
    Batista, Ana
    Kirkpatrick, Nathaniel
    Jung, Keehoon
    Snuderl, Matija
    Muzikansky, Alona
    Stubenrauch, Kay G.
    Krieter, Oliver
    Wakimoto, Hiroaki
    Xu, Lei
    Munn, Lance L.
    Duda, Dan
    Fukumura, Dai
    Batchelor, Tracy
    Jain, Rakesh
    NEURO-ONCOLOGY, 2016, 18 : 95 - 95
  • [6] Anti-tumor efficacy of Cloretazine (VNP40101M) alone and in combination with fludarabine in murine tumor and human xenograft tumor models
    Li-mou Zheng
    Zujin Li
    Lanzhen Liu
    Bai Louis Song
    Ivan King
    Cancer Chemotherapy and Pharmacology, 2007, 60 : 45 - 51
  • [7] Anti-tumor efficacy of Cloretazine (VNP40101M) alone and in combination with fludarabine in murine tumor and human xenograft tumor models
    Zheng, Li-mou
    Li, Zujin
    Liu, Lanzhen
    Song, Bai Louis
    King, Ivan
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2007, 60 (01) : 45 - 51
  • [8] Anti-tumor efficacy of cloretazine (VNP40101M) alone and in combination with fludarabine and cytarabine in murine tumor and human xenograft tumor models
    Liu, Lanzhen
    Li, Zujin
    Song, Bai L.
    King, Ivan
    Zheng, Li-Mou
    CANCER RESEARCH, 2006, 66 (08)
  • [9] Potent synergistic anti-tumor activity of a novel humanized anti-HER2 antibody hersintuzumab in combination with trastuzumab in xenograft models
    Fariba Shiravi
    Mehdi Mohammadi
    Forough Golsaz-Shirazi
    Tannaz Bahadori
    Mohammad Ali Judaki
    Forough Fatemi
    Hengameh Ahmadi Zare
    Farzaneh Notash Haghighat
    Maryam Mobini
    Mahmood Jeddi-Tehrani
    Mohammad Mehdi Amiri
    Fazel Shokri
    Investigational New Drugs, 2021, 39 : 697 - 704
  • [10] Potent synergistic anti-tumor activity of a novel humanized anti-HER2 antibody hersintuzumab in combination with trastuzumab in xenograft models
    Shiravi, Fariba
    Mohammadi, Mehdi
    Golsaz-Shirazi, Forough
    Bahadori, Tannaz
    Judaki, Mohammad Ali
    Fatemi, Forough
    Zare, Hengameh Ahmadi
    Haghighat, Farzaneh Notash
    Mobini, Maryam
    Jeddi-Tehrani, Mahmood
    Amiri, Mohammad Mehdi
    Shokri, Fazel
    INVESTIGATIONAL NEW DRUGS, 2021, 39 (03) : 697 - 704
12345