Synthesis and characterisation of yittrium doped cerium oxide nanoparticles and their efficient antibacterial application invitro against gram-positive and gram-negative pathogens

The point of the study is to synthesize Ce1-xYtxO2 (X = 0.00, 0.02, 0.04, 0.06, and 0.08), and to characterize it. A chemical precipitation procedure was used to synthesize the yttrium (Yt) doped cerium oxide (CeO2) powders. Powder X-ray diffraction (XRD) analysis revealed that the phase pure cubic structured CeO2 crystal system exists. The Rietveld refining method has been used to look into the comprehensive structural examination of produced materials. Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) were used to examine the surface morphology and elemental content of the produced materials (EDAX). FTIR spectroscopy has revealed the presence of vibrational linkages linked to distinct functional groups. UV-Vis spectroscopy was used to look at the energy gap of synthetic materials. Photoluminescence (PL) analysis was used to investigate the luminescence activity of synthesized materials. Synthesized materials under 380 nm excitation produced a light-green emission at around 516 nm. In addition, the electron density distribution in synthetic materials has been achieved. Furthermore, Pseudomonas aeruginosa and Corynebacterium diphtheria were used to test the antibacterial activity of produced compounds. Hemolysis inquiry was then used to look at the destruction of human red blood cells. The 4% Yt3+ dopant level was shown to be the optimal level of Yt3+ dopant in the CeO2 host lattice in all of the characterization. The current study opens a viable path for developing efficient biomedical materials.Copyright (c) 2022 Elsevier Ltd. All rights reserved. Selection and peer-review under responsibility of scientific committee of the International Conference on Advanced Materials and Mechanical Characterization (ICAMMC 2021).