Synthesis and antimicrobial activity of 4-oxothiazolidines

被引：0

作者：

Patel, HD ^{[1
]}

Mistry, BD

Desai, KR

机构：

[1] S Gujarat Univ, Dept Chem, Surat 295001, India

[2] St Xaviers Coll, Dept Chem, Ahmedabad 380009, Gujarat, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2002年 / 11卷 / 03期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various 4-oxothiazolidines III(a-j), 5-methyl-4-oxothiazolidines IV(a-j) and 5-ethanoic acid -4- oxothiazolidines V(a-j) were prepared by reacting N-[1-aza-2-(substituted phenyl) vinyl] (2-amino-5-nitro phenyl) carboxamides II(a-j) with thioglycollic acid, thiolactic acid and thiomalic acid respectively, and these N-[1-aza-2-(substituted phenyl) vinyl] (2-amino-5-nitro phenyl) carboxamides II(a-j) were synthesised by hydrolysis of W[1-aza-2-(substituted phenyl) vinyl] [2-acetamido-5-nitro phenyl] carboxamides-I(a-j). Reaction between N-amino-(2-amino-5-nitro phenyl) carboxamide and different aldehydes gives N-[1 -aza-2-(substituted phenyl) vinyl] (2-acetamido-5-nitro phenyl) carboxamides-I (a-j). These compounds were characterized on the basis of elemental and spectral analysis. All the newly synthesized compounds were tested for their antimicrobial activity.

引用

页码：233 / 236

页数：4