Why is Deinococcus radiodurans so resistant to ionizing radiation?

被引：236
作者：
Battista, JR
Earl, AM
Park, MJ
机构：
[1] Louisiana State Univ, Dept Biol Sci, Baton Rouge, LA 70803 USA
[2] A&M Coll, Baton Rouge, LA 70803 USA
来源：
TRENDS IN MICROBIOLOGY | 1999年 / 7卷 / 09期
基金：
美国国家科学基金会;
关键词：
D O I：
10.1016/S0966-842X(99)01566-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
When exponential-phase cultures of Deinococcus radiodurans are exposed to a 5000-Gray dose of gamma radiation, individual cells suffer massive DNA damage. Despite this insult to their genetic integrity, these cells survive without loss of viability or evidence of mutation, repairing the damage by as-yet-poorly-understood mechanisms.
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页码：362 / 365
页数：4
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