Design of a passive flow regulator using a genetic algorithm

被引：5

作者：

Dumont-Fillon, D. ^{[1
]}

Hannebelle, M. ^{[2
]}

Van Lintel, H. ^{[2
]}

Chappel, E. ^{[1
]}

机构：

[1] Debiotech SA, 28 Ave Sevelin, CH-1004 Lausanne, Switzerland

[2] Swiss Fed Inst Technol, LMIS4, CH-1015 Lausanne, Switzerland

来源：

PROCEEDINGS OF THE 30TH ANNIVERSARY EUROSENSORS CONFERENCE - EUROSENSORS 2016 | 2016年 / 168卷

关键词：

Valve; flow regulator; optimization; genetic algorithm; hydrocephalus; drug delivery;

D O I：

10.1016/j.proeng.2016.11.329

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Passive flow regulators are usually intended to deliver or drain a fluid at a constant rate independently from pressure variations. Microfluidic devices made of a stack of two plates are considered here: the first plate comprises a flexible silicon membrane having through holes while the second plate is a rigid substrate with a cavity, an outlet hole and pillars aligned with the through holes of the membrane. The liquid flows through the holes etched in the membrane and through the small gap between the bottom of the membrane and the pillars: each hole can therefore be considered as a valve which progressively closes as the pressure increases, thus leading to a non-linear fluidic behaviour. FEM simulations have been performed to ensure a constant flow rate in the specified range of pressure. To make the design reliable, the device characteristics have been optimized using an evolutionary algorithm. The fitness function notably takes into account machining and alignment tolerances. Typical designs dedicated to drug delivery and hydrocephalus treatment are discussed. (C) 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.

引用

页码：1016 / 1019

页数：4