Telomere shortening, ageing, and chromosome damage

被引：9

作者：

KormannBortolotto, MH ^{[1
]}

Borsatto, B ^{[1
]}

Smith, MDC ^{[1
]}

机构：

[1] UNIFESP, ESCOLA PAULISTA MED, DISCIPLINA GENET, DEPT MORFOL, BR-04023900 SAO PAULO, BRAZIL

来源：

MECHANISMS OF AGEING AND DEVELOPMENT | 1996年 / 89卷 / 01期

基金：

巴西圣保罗研究基金会;

关键词：

ageing; chromosome instability; telomere shortening;

D O I：

10.1016/0047-6374(96)01742-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A relationship between telomere shortening and ageing has been established. A series of young and elderly healthy donors, Alzheimer disease patients, young and old Down's syndrome individuals were cytogenetically analyzed. No preferential damage in distal bands was seen in age-related chromosome instability.

引用

页码：45 / 49

页数：5

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