Imaging and histological appearance of pleomorphic hyalinizing angiectatic tumors: A case series and literature review

被引:8
作者
Jaramillo, Couger Jimenez [1 ]
Wojcik, John [2 ]
Weber, Kristy [3 ]
Sebro, Ronnie [1 ]
机构
[1] Univ Penn, Dept Radiol, 3400 Spruce St, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Pathol, Philadelphia, PA 19104 USA
[3] Univ Penn, Dept Orthoped Surg, Philadelphia, PA 19104 USA
关键词
pleomorphic hyalinizing angiectatic tumors; magnetic resonance imaging; computed tomography; ultrasound; positron emission tomography/computed tomography; FINE-NEEDLE-ASPIRATION; OF-THE-LITERATURE; SOFT PARTS; MYXOFIBROSARCOMA; COMPONENT; CYTOLOGY; FEATURES; TISSUE; PHAT;
D O I
10.3892/ol.2018.7929
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Pleomorphic hyalinizing angiectatic tumors (PHATs) are rare mesenchymal soft tissue tumors of uncertain lineage and intermediate malignancy. The present study assesses two cases of PHAT and discusses the histological and immunophenotypical features, as well as the imaging appearance of these tumors on ultrasound, computed tomography (CT), magnetic resonance imaging and positron emission tomography/CT scans. The current study also reviews the literature and discusses the clinical management of these tumors. Wide local excision with tumor free margins is the current recommended treatment for PHAT. Surgical excision may be combined with low-dose radiation to reduce the risk of local recurrence. Patients should be followed up with serial imaging, as PHAT lesions tend to recur locally.
引用
收藏
页码:4720 / 4730
页数:11
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