Diabetes Management in Older Adults With Chronic Kidney Disease

被引：19
作者：
Clemens, Kristin K. [1 ,2 ,3 ,4 ,5 ]
O'Regan, Niamh [3 ,5 ,6 ]
Rhee, Jinnie J. [7 ]
机构：
[1] Western Univ, Dept Med, Div Endocrinol, London, ON, Canada
[2] Western Univ, Dept Epidemiol & Biostat, London, ON, Canada
[3] St Josephs Hlth Care London, London, ON, Canada
[4] Inst Clin Evaluat Sci, London, ON, Canada
[5] Lawson Hlth Res Inst, London, ON, Canada
[6] Western Univ, Dept Med, Div Geriatr Med, London, ON, Canada
[7] Stanford Univ, Sch Med, Dept Med, Div Nephrol, Stanford, CA 94305 USA
来源：
CURRENT DIABETES REPORTS | 2019年 / 19卷 / 03期
基金：
加拿大健康研究院; 美国国家卫生研究院;
关键词：
Diabetes; Older adults; Chronic kidney disease; Antihyperglycemic medications; Frailty; Hypoglycemia; Comorbidity; CHRONIC RENAL-INSUFFICIENCY; GLOMERULAR-FILTRATION-RATE; GLYCEMIC CONTROL; COGNITIVE FUNCTION; CARDIOVASCULAR-DISEASE; SERUM CREATININE; ELDERLY-PATIENTS; DOUBLE-BLIND; HYPOGLYCEMIA; INSULIN;
D O I：
10.1007/s11892-019-1128-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Purpose of ReviewOlder adults often live with chronic disease including diabetes and its complications. In this review, we examine the complexity and heterogeneity of older adults with diabetes and chronic kidney disease, explore the nuances in their diabetes-related monitoring, and discuss their best diabetes management.Recent FindingsAlthough there remains an overall lack of studies in older adults with diabetes and chronic kidney disease, recent reports have highlighted their vulnerabilities. These individuals face an increased risk of cognitive impairment and dementia, frailty, dysglycemia, polypharmacy, declining kidney function, and acute kidney injury. Their diabetes management should focus upon safer antihyperglycemic medications, close monitoring, and care individualization.SummaryOlder adults with diabetes and chronic kidney disease are a complex population who requires careful diabetes management and monitoring. Research efforts might focus on improving the care and outcomes of these patients.
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页数：11
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