An approach to total synthesis of the cylindricine B pyridoquinoline subclass of tricyclic marine ascidian alkaloids

被引：22

作者：

Chao, Wenchun ^{[1
]}

Mahajan, Yogesh R. ^{[1
]}

Weinreb, Steven M. ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 23期

基金：

美国国家卫生研究院;

关键词：

alkaloids; ring closing metathesis; hetero Diels-Alder reaction; N-acyliminium ion; nitrogen heterocycles; cycloaddition;

D O I：

10.1016/j.tetlet.2006.03.195

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Employing an intramolecular N-acylketiminium ion/olefin hetero Diels-Alder reaction, and a ring closing metathesis of a vinyl chloride as pivotal steps, it is possible to directly access the pyridoquinoline tricyclic ring system of the marine alkaloids cylindrines B and J. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3815 / 3818

页数：4

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