Based on the established full-car active suspension model, fuzzy control theory was combined with neural network control, the fuzzy neural network control system of vehicle active suspension was designed, simulation and analysis of random road input and sine wave input were carried on. The results show that, by comparison with the traditional suspension system, the peak and standard deviation of vehicle mass vertical acceleration decreased by 55.38% and 59.04%, the peak of vehicle mass vertical acceleration decreased by 49.96% when vehicle go through the sine wave at the speed of 5m/s, the ride comfort was improved obviously.