Prenatal diethylstilbestrol exposure and breast cancer

被引：1
作者：
Frigo, S. [1 ]
Malina, C. [1 ]
Mathelin, C. [1 ]
机构：
[1] CHRU Strasbourg, Unite Senol, F-67200 Strasbourg, France
来源：
GYNECOLOGIE OBSTETRIQUE & FERTILITE | 2012年 / 40卷 / 12期
关键词：
Breast cancer; Diethylstilbestrol; In utero exposure; Screening; IN-UTERO; RISK;
D O I：
10.1016/j.gyobfe.2012.09.005
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Diethylstilbestrol (DES) is a synthetic estrogen prescribed to prevent miscarriages until 1977. Its role in the development of vaginal adenocarcinoma and cervical dysplasia is known and screening codified. Recent cohort studies show that exposure to DES in utero increases breast cancer risk especially after 40 years. This article reports the observation of a breast cancer of exceptional gravity in a patient exposed to DES in utero. It details the risk of breast cancer for "DES daughters" and support possible screening modalities. (C) 2012 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：784 / 786
页数：3
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