Emerging functional roles of cathepsin E

被引：33

作者：

Zaidi, Nousheen ^{[1
,2
]}

Hermann, Clemens ^{[1
,2
]}

Herrmann, Timo ^{[1
,2
]}

Kalbacher, Hubert ^{[1
,2
]}

机构：

[1] Univ Tubingen, Med & Nat Sci Res Ctr, D-72074 Tubingen, Germany

[2] Univ Tubingen, Interfacultary Inst Biochem, D-72074 Tubingen, Germany

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2008年 / 377卷 / 02期

关键词：

Cathepsin E; Aspartic protease;

D O I：

10.1016/j.bbrc.2008.10.034

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cathepsin E is an intracellular aspartic protease of the endolysosomal pathway. It has been implicated in several physiological and pathological processes however, its exact functional role is yet to be elucidated. The present review gives an account of the Major physiological functions that are associated to cathepsin E by various research groups and highlights the conditions developed in cathepsin E deficiency or the conditions where overexpression of cathepsin E is observed. (C) 2008 Elsevier Inc. All rights reserved.

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页码：327 / 330

页数：4

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