Breakup of finite thickness viscous shell microbubbles by ultrasound: A simplified zero-thickness shell model

被引:10
作者
Hsiao, Chao-Tsung [1 ]
Chahine, Georges L. [1 ]
机构
[1] Dynaflow Inc, Jessup, MD 20794 USA
关键词
GENE DELIVERY; BUBBLE; DESTRUCTION; COLLAPSE;
D O I
10.1121/1.4792492
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
A simplified three-dimensional (3-D) zero-thickness shell model was developed to recover the non-spherical response of thick-shelled encapsulated microbubbles subjected to ultrasound excitation. The model was validated by comparison with previously developed models and was then used to study the mechanism of bubble break-up during non-spherical deformations resulting from the presence of a nearby rigid boundary. The effects of the shell thickness and the bubble standoff distance from the solid wall on the bubble break-up were studied parametrically for a fixed insonification frequency and amplitude. A diagram of bubble shapes versus the normalized shell thickness and wall standoff was derived, and the potential bubble shapes at break-up from reentrant jets were categorized resulting in four distinct zones. (C) 2013 Acoustical Society of America.
引用
收藏
页码:1897 / 1910
页数:14
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