Pharmacovigilance and Biomedical Informatics: A Model for Future Development

被引：36

作者：

Beninger, Paul ^{[1
]}

Ibara, Michael A. ^{[2
]}

机构：

[1] Tufts Univ, Sch Med, Publ Hlth & Community Med, 136 Harrison Ave, Boston, MA 02111 USA

[2] Clin Data Interchange Stand Consortium, Princeton, NJ USA

来源：

CLINICAL THERAPEUTICS | 2016年 / 38卷 / 12期

关键词：

adverse drug reactions; biomedical informatics; Internet; pharmacoepidemiology; pharmacovigilance;

D O I：

10.1016/j.clinthera.2016.11.006

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Purpose: The discipline of pharmacovigilance is rooted in the aftermath of the thalidomide tragedy of 1961. It has evolved as a result of collaborative efforts by many individuals and organizations, including physicians, patients, Health Authorities, universities, industry, the World Health Organization, the Council for International Organizations of Medical Sciences, and the International Conference on Harmonisation. Biomedical informatics is rooted in technologically based methodologies and has evolved at the speed of computer technology. The purpose of this review is to bring a novel lens to pharmacovigilance, looking at the evolution and development of the field of pharmacovigilance from the perspective of biomedical informatics, with the explicit goal of providing a foundation for discussion of the future direction of pharmacovigilance as a discipline. Methods: For this review, we searched [publication trend for the log(10) value of the numbers of publications identified in PubMed] using the key words [informatics (INF), pharmacovigilance (PV), pharmacovigilance ID informatics (PV (sic) INF)], for [study types] articles published between [1994-2015]. We manually searched the reference lists of identified articles for additional information.

引用

页码：2514 / 2525

页数：12

共 45 条

[1]

AMIA Ethical L Social Issues Working Group, ETH LEG SOC ISS WORK

[2] Toward a complete dataset of drug-drug interaction information from publicly available sources [J].

Ayvaz, Serkan ;

Horn, John ;

Hassanzadeh, Oktie ;

Zhu, Qian ;

Stan, Johann ;

Tatonetti, Nicholas P. ;

Vilar, Santiago ;

Brochhausen, Mathias ;

Samwald, Matthias ;

Rastegar-Mojarad, Majid ;

Dumontier, Michel ;

Boyce, Richard D. .

JOURNAL OF BIOMEDICAL INFORMATICS, 2015, 55 :206-217

[3]

Bernardo JM, BAYESIAN METHODS PHA

[4] What is biomedical informatics? [J].

Bernstam, Elmer V. ;

Smith, Jack W. ;

Johnson, Todd R. .

JOURNAL OF BIOMEDICAL INFORMATICS, 2010, 43 (01) :104-110

[5]

Biesdorf S, HEALTHCARES DIGITAL

[6] THE PROBLEM OF SOCIAL COST [J].

COASE, RH .

JOURNAL OF LAW & ECONOMICS, 1960, 3 (OCT) :1-44

[7]

Cobert B., UPDATE DRUG SAFETY C

[8]

Crook J., APPLE ACQUIRED GLIIM

[9] Ongoing Challenges in Pharmacovigilance [J].

Dal Pan, Gerald J. .

DRUG SAFETY, 2014, 37 (01) :1-8

[10] Machine Learning and the Profession of Medicine [J].

Darcy, Alison M. ;

Louie, Alan K. ;

Roberts, Laura Weiss .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2016, 315 (06) :551-552

← 1 2 3 4 5 →