A coherent model for turbid imaging with confocal microscopy

被引:3
作者
Glazowski, Christopher E. [1 ]
Zavislan, James [1 ]
机构
[1] Univ Rochester, Inst Opt, Rochester, NY 14627 USA
来源
BIOMEDICAL OPTICS EXPRESS | 2013年 / 4卷 / 04期
关键词
SKIN;
D O I
10.1364/BOE.4.000500
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We present an engineering model of coherent imaging within a turbid volume, such as human tissues, with a confocal microscope. The model is built to analyze the statistical effect of aberrations and multiply scattered light on the resulting image. Numerical modeling of theory is compared with experimental results. We describe the construction of a stable phantom that represents the statistical effect of object turbidity on the image recorded. The model and phantom can serve as basis for system optimization in turbid imaging. (C) 2013 Optical Society of America
引用
收藏
页码:500 / 513
页数:14
相关论文
共 20 条
  • [1] Reflectance Confocal Microscopy in the Daily Practice
    Ahlgrimm-Siess, Verena
    Hofmann-Wellenhof, Rainer
    Cao, Theresa
    Oliviero, Margaret
    Scope, Alon
    Rabinovitz, Harold S.
    [J]. SEMINARS IN CUTANEOUS MEDICINE AND SURGERY, 2009, 28 (03) : 180 - 189
  • [2] [Anonymous], 1990, CONFOCAL MICROSCOPY
  • [3] [Anonymous], 2000, MODERN OPTICAL ENG
  • [4] A REVIEW OF THE OPTICAL-PROPERTIES OF BIOLOGICAL TISSUES
    CHEONG, WF
    PRAHL, SA
    WELCH, AJ
    [J]. IEEE JOURNAL OF QUANTUM ELECTRONICS, 1990, 26 (12) : 2166 - 2185
  • [5] Optimal detection pinhole for lowering speckle noise while maintaining adequate optical sectioning in confocal reflectance microscopes
    Glazowski, Christopher
    Rajadhyaksha, Milind
    [J]. JOURNAL OF BIOMEDICAL OPTICS, 2012, 17 (08)
  • [6] Coherent pupil engineered scanning reflectance confocal microscope (SRCM) for turbid imaging
    Glazowski, Christopher
    Zavislan, James M.
    [J]. THREE-DIMENSIONAL AND MULTIDIMENSIONAL MICROSCOPY: IMAGE ACQUISITION AND PROCESSING XVII, 2010, 7570
  • [7] Gonzalez S., 2008, International Journal of Cosmetic Science, V30, P1, DOI 10.1111/j.1468-2494.2008.00406.x
  • [8] Goodman J., 1996, Opt. Eng
  • [9] SOME FUNDAMENTAL PROPERTIES OF SPECKLE
    GOODMAN, JW
    [J]. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA, 1976, 66 (11) : 1145 - 1150
  • [10] Ballistic and diffuse light detection in confocal and heterodyne imaging systems
    Kempe, M
    Genack, AZ
    Rudolph, W
    Dorn, P
    [J]. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1997, 14 (01): : 216 - 223