Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia

被引：107

作者：

Khunti, Sachin ^{[2
]}

Khunti, Kamlesh ^{[3
]}

Seidu, Samuel ^{[1
]}

机构：

[1] Univ Leicester, Diabet Res Ctr, Leicester Gen Hosp, Gwendolen Rd, Leicester LE5 4PW, Leics, England

[2] Barts & London Queen Marys Sch Med & Dent, Sch Med & Dent, London, England

[3] Univ Leicester, Diabet Res Ctr, Leicester, Leics, England

来源：

THERAPEUTIC ADVANCES IN ENDOCRINOLOGY AND METABOLISM | 2019年 / 10卷

关键词：

Therapeutic inertia; type; 2; diabetes; prevalence; causes; patient level; providers; system level; oral antihyperglycaemic drugs; insulin; CLINICAL INERTIA; PRIMARY-CARE; TREATMENT INTENSIFICATION; GLYCEMIC CONTROL; FOLLOW-UP; GLUCOSE CONTROL; PEOPLE; MANAGEMENT; INSULIN; METFORMIN;

D O I：

10.1177/2042018819844694

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Early glycaemic control leads to better outcomes, including a reduction in long-term macrovascular and microvascular complications. Despite good-quality evidence, glycaemic control has been shown to be inadequate globally. Therapeutic inertia has been shown present in all stages of treatment intensification, from the first oral antihyperglycaemic drug (OAD), all the way to the initiation of insulin. The causes and possible solutions to the problem of therapeutic inertia are complex but can be understood better when viewed from the perspective of the providers [healthcare professionals (HCPs)], patients and healthcare systems. In this review, we will discuss the possible aetiologies, consequences and solutions of therapeutic inertia, drawing upon evidence from published literature on the subject of type 2 diabetes.

引用

页数：11

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