Organic UV filters in personal care products in Switzerland: A survey of occurrence and concentrations

被引:91
作者
Manova, Eva [1 ]
von Goetz, Natalie [1 ]
Hauri, Urs [2 ]
Bogdal, Christian [1 ]
Hungerbuehler, Konrad [1 ]
机构
[1] ETH, Inst Chem & Bioengn, CH-8093 Zurich, Switzerland
[2] State Lab Basel City, Basel, Switzerland
关键词
Organic UV filters; Concentration; Personal care products; Endocrine disrupting chemicals; 3-BENZYLIDENE CAMPHOR; ULTRAVIOLET ABSORBERS; ESTROGENIC ACTIVITY; ANDROGEN RECEPTORS; SUNSCREEN USE; SUN EXPOSURE; TOXICITY; BINDING;
D O I
10.1016/j.ijheh.2012.08.003
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Organic ultraviolet (UV) filters are a group of compounds designed to absorb UV radiation and hence protect our skin against UV-induced damage. Apart from traditional sunscreens, they can be found in many other categories of personal care products (PCPs). These include skin care, facial makeup and lip care products, which are often used simultaneously, and on a regular basis. The frequency of occurrence as well as concentrations of organic UV filters contained in PCPs change over time. Furthermore, in Switzerland the exact UV filter concentrations are confidential. To date, only limited data are available for the levels of organic UV filters in PCPs, and these data refer mainly to sunscreens. In this paper, we provide an up-to-date frequency of occurrence and concentrations of organic UV filters in PCPs, including for the first time PCPs used in everyday life. A total of 116 PCPs was selected on the basis of a product-use questionnaire and distributed among seven PCP categories: lip care products, lipsticks, face creams, liquid makeup foundations, aftershaves, hand creams, and sunscreens. Concentrations of 22 organic UV filters were measured in the selected PCPs. The most frequently occurring UV filters were butyl methoxydibenzoyl-methane (BMBM) detected in 82 products (71%), ethylhexyl methoxycinnamate (EHMC) in 59 products (51%) and octocrylene (OCT) in 50 products (43%). BMBM, EHMC and OCT concentrations averaged 2.6%, 4.0%, and 6.0%, respectively. Overall, UV filter concentrations in PCPs applied regularly throughout the year can be as high as those in sunscreens that are primarily used for sun protection and hence applied only on selected days. PCPs that are used on a regular basis, and often simultaneously, thus represent an important and, as yet, unquantified source of UV filter exposure. This study provides essential information for aggregate exposure assessments that combine data on concentrations of individual UV filters widely used in a variety of PCP categories. (C) 2012 Elsevier GmbH. All rights reserved.
引用
收藏
页码:508 / 514
页数:7
相关论文
共 45 条
  • [1] Lack of binding to isolated estrogen or androgen receptors, and inactivity in the immature rat uterotrophic assay, of the ultraviolet sunscreen filters Tinosorb M-active and Tinosorb S
    Ashby, J
    Tinwell, H
    Plautz, J
    Twomey, K
    Lefevre, PA
    [J]. REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2001, 34 (03) : 287 - 291
  • [2] Sunscreen use and increased duration of intentional sun exposure:: Still a burning issue
    Autier, Philippe
    Boniol, Mathieu
    Dore, Jean-Francois
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2007, 121 (01) : 1 - 5
  • [3] Effects of pre- and postnatal exposure to the UV-filter Octyl Methoxycinnamate (OMC) on the reproductive, auditory and neurological development of rat offspring
    Axelstad, Marta
    Boberg, Julie
    Hougaard, Karin Sorig
    Christiansen, Sofie
    Jacobsen, Pernille Rosenskjold
    Mandrup, Karen Riiber
    Nellemann, Christine
    Lund, Soren Peter
    Hass, Ulla
    [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2011, 250 (03) : 278 - 290
  • [4] Organic UV filter concentrations in marine mussels from French coastal regions
    Bachelot, Morgane
    Li, Zhi
    Munaron, Dominique
    Le Gall, Patrik
    Casellas, Claude
    Fenet, Helene
    Gomez, Elena
    [J]. SCIENCE OF THE TOTAL ENVIRONMENT, 2012, 420 : 273 - 279
  • [5] The 500 Dalton rule for the skin penetration of chemical compounds and drugs
    Bos, JD
    Meinardi, MMHM
    [J]. EXPERIMENTAL DERMATOLOGY, 2000, 9 (03) : 165 - 169
  • [6] Photopatch testing of 1155 patients: results of the UK multicentre photopatch study group
    Bryden, A. M.
    Moseley, H.
    Ibbotson, S. H.
    Chowdhury, M. M. U.
    Beck, M. H.
    Bourke, J.
    English, J.
    Farr, P.
    Foulds, I. S.
    Gawkrodger, D. J.
    George, S.
    Orton, D. I.
    Shaw, S.
    McFadden, J.
    Norris, P.
    Podmore, P.
    Powell, S.
    Rhodes, L. E.
    Sansom, J.
    Wilkinson, M.
    van Weelden, H.
    Ferguson, J.
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2006, 155 (04) : 737 - 747
  • [7] Toxicity and phototoxicity of chemical sun filters
    Butt, ST
    Christensen, T
    [J]. RADIATION PROTECTION DOSIMETRY, 2000, 91 (1-3) : 283 - 286
  • [8] Council of the European Communities, 1976, Offic J L., V262, P169
  • [9] Sunscreens cause coral bleaching by promoting viral infections
    Danovaro, Roberto
    Bongiorni, Lucia
    Corinaldesi, Cinzia
    Giovannelli, Donato
    Damiani, Elisabetta
    Astolfi, Paola
    Greci, Lucedio
    Pusceddu, Antonio
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2008, 116 (04) : 441 - 447
  • [10] Endocrine Disruptors and Asthma-Associated Chemicals in Consumer Products
    Dodson, Robin E.
    Nishioka, Marcia
    Standley, Laurel J.
    Perovich, Laura J.
    Brody, Julia Green
    Rudel, Ruthann A.
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2012, 120 (07) : 935 - 943