Graft detachment and rebubbling rate in Descemet membrane endothelial keratoplasty

被引:67
作者
Parekh, Mohit [1 ,2 ]
Leon, Pia [3 ,4 ,5 ]
Ruzza, Alessandro [1 ]
Borroni, Davide [6 ,7 ]
Ferrari, Stefano [1 ]
Ponzin, Diego [1 ]
Romano, Vito [8 ]
机构
[1] Veneto Eye Bank Fdn, Int Ctr Ocular Physiopathol, Via Paccagnella 11, I-30174 Venice, Italy
[2] Univ Padua, Sch Biomed, Dept Mol Med, Padua, Italy
[3] SS Giovanni & Paolo Hosp, Dept Ophthalmol, Venice, Italy
[4] Villa Igea Hosp, Dept Ophthalmol, Forli, Italy
[5] Ist Int Ric & Formaz Oftalmol IRFO, Forli, Italy
[6] Riga Stradins Univ, Dept Ophthalmol, Riga, Latvia
[7] Riga Stradins Univ, Dept Genet, Riga, Latvia
[8] Moorfields Eye Hosp NHS Fdn Trust, London, England
关键词
DMEK; rebubble rate; graft detachment; CORNEAL CLEARANCE; DMEK GRAFTS; CELL-LOSS; MANAGEMENT; SURVIVAL; OUTCOMES; PHACOEMULSIFICATION; IMPLANTATION; SURGERY; TISSUES;
D O I
10.1016/j.survophthal.2017.07.003
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Descemet membrane endothelial keratoplasty (DMEK) is a selective replacement of dysfunctional endothelium with healthy donor Descemet membrane and endothelium. Although the donor preparation and surgical methods still remain a challenge, DMEK is gaining popularity in terms of early rehabilitation and visual outcomes. New and improved donor preparation techniques like prestripped DMEK tissues are being taken up rapidly because of less manipulation that is required in the surgical theatre. Donor graft delivery in the recipient eye has also been improved because of new products like prestripped and preloaded membranes. As DMEK is at its budding stage, only early outcomes have been known so far. Early graft detachment, rebubbling rates, and primary failures are still being studied in DMEK. As there are different techniques that are currently used for preparation and injection of the graft, it becomes difficult to judge the results based on specific inclusion and exclusion criteria. Graft detachment and rebubbling rates have been a huge challenge both during the surgery and also while reporting postoperative data. We highlight the importance of defining graft detachment and rebubbling rates and their surgical relevance, which may also have an impact on graft preparation and insertion techniques. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码:245 / 250
页数:6
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