Synthesis of the bicyclic core of the nucleoside antibiotic octosyl acid A

被引：6

作者：

More, JD ^{[1
]}

Finney, NS ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 06期

关键词：

D O I：

10.1021/jo052025s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The bicyclic core of octosyl acid A has been prepared using a diastereoselective acetylide addition and 6-endo selenoetherification as key steps. A detailed study of the selenoetherification reaction and difficulties encountered in the conversion of a phenyl group to a carboxylic acid will be discussed.

引用

页码：2236 / 2241

页数：6

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