Bowel exposure in rectal cancer IMRT using prone, supine, or a belly board

被引:39
作者
Nijkamp, Jasper [1 ]
Doodeman, Barry [1 ]
Marijnen, Corrie [2 ]
Vincent, Andrew [3 ]
van Vliet-Vroegindeweij, Corine [1 ]
机构
[1] Antoni van Leeuwenhoek Hosp, Dept Radiat Oncol, Netherlands Canc Inst, NL-1066 CX Amsterdam, Netherlands
[2] Leiden Univ, Dept Clin Oncol, Med Ctr, NL-2300 RA Leiden, Netherlands
[3] Netherlands Canc Inst, Dept Biometr, Amsterdam, Netherlands
关键词
Belly board; Bowel exposure; Rectal cancer; IMRT; PREOPERATIVE RADIATION-THERAPY; INTENSITY-MODULATED RADIOTHERAPY; TOTAL MESORECTAL EXCISION; DOSE-VOLUME RELATIONSHIP; PELVIC IRRADIATION; RANDOMIZED-TRIAL; POSTOPERATIVE RADIOTHERAPY; SPHINCTER PRESERVATION; FOLLOW-UP; CHEMORADIOTHERAPY;
D O I
10.1016/j.radonc.2011.05.076
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: To investigate bowel exposure using prone, supine, or two different belly boards for rectal cancer intensity modulated RT plans using a full bladder protocol. Methods and materials: For 11 volunteers four MR scans were acquired, on a flat table in prone, supine, and on two different belly boards (IT-V Medizintechnik GmbH (R) (BB1) and CIVCO (R) (BB2)), using a full bladder protocol. On each scan a 25 x 2 Gy IMRT plan was calculated. Results: BB2 led to an average bowel area volume reduction of 20-30% at any dose level compared to prone. BB1 showed a smaller dose reduction effect, while no differences between prone and supine were found. Differences between BB2 and prone, supine or BB1 were significant up to a level of respectively, 45,35, and 30 Gy. The reducing effect varied among individuals, except for the 50 Gy region, where no effect was found. An increase in bladder volume of 100 cc led to a significant bowel area V15 reduction of 16% independent of scan type. Conclusions: In the low and intermediate dose region a belly board still attributes to a significant bowel dose reduction when using IMRT and a full bladder protocol. A larger bladder volume resulted in a significant decreased bowel area dose. (C) 2011 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 102 (2012) 22-29
引用
收藏
页码:22 / 29
页数:8
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