The role of visual information in the control of scleral matrix biology in myopia

被引:39
作者
McBrien, NA [1 ]
Gentle, A [1 ]
机构
[1] Univ Melbourne, Dept Optometry & Vis Sci, Melbourne, Vic 3010, Australia
关键词
sclera; scleral remodelling; myopia; emmetropisation; eye growth;
D O I
10.1076/ceyr.23.5.313.5440
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Changes in eye size during the development of refractive error are accompanied by alterations in scleral biochemistry in both humans and animal models of myopia. This review discusses more recent data on scleral changes in mammalian models of myopia and considers the role of visual information in the control of scleral matrix biology. These visually-driven changes in scleral biochemistry are placed in the context of both the emmetropisation process and the abnormal enlargement of the eye that is characteristic of human high myopia.
引用
收藏
页码:313 / 319
页数:7
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