Ontological and Reproductive Outcomes of Abdominal Radical Trachelectomy

被引:7
作者
Yoshino, Ai [1 ]
Kobayashi, Eiji [1 ]
Kodama, Michiko [1 ]
Hashimoto, Kae [1 ]
Ueda, Yutaka [1 ]
Sawada, Kenjiro [1 ]
Tomimatsu, Takuji [1 ]
Kimura, Tadashi [1 ]
机构
[1] Osaka Univ, Dept Obstet & Gynecol, Grad Sch Med, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan
关键词
Abdominal radical trachelectomy; cervical cancer; fertility-sparing; fertility preservation; radical hysterectomy; STAGE CERVICAL-CANCER; FERTILITY-SPARING SURGERY; CONSERVATIVE MANAGEMENT; PATHOLOGICAL OUTCOMES; HYSTERECTOMY; PREGNANCY; SERIES; WOMEN;
D O I
10.21873/anticanres.14615
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background/Aim: There is an increasing demand for preserving the fertility of young women impacted with early-stage cervical cancer. The aim of this study is to evaluate the oncological and reproductive outcomes of abdominal radical trachelectomy (ART). Patients and Methods: We retrospectively reviewed patients with FIGO stageIA2-IB1 cervical cancer who underwent ART from 2007 to 2018. We also compared the oncological prognosis between the patients who underwent ART and radical hysterectomy (RH). Results: A total of 42 patients underwent ART. During median follow-up 62.5 months, there were 4 (9.5%) recurrences and 1 (2.4%) death. As for tumors <= 2 cm, the 5-year recurrence-free survival (RFS) rate and overall survival (OS) rate for patients who underwent ART was similar to those who underwent RH (89.8% vs. 92.7%, p.1.42 and 97.3% vs. 95.0%, p=0.44, respectively). Nineteen patients attempted to conceive and seven of them were successful. There was one case of a first-trimester miscarriage, two cases of preterm delivery, three cases of full-term delivery and one ongoing pregnancy. Conclusion: ART could be a feasible alternative to RH for patients with tumors <= 2 cm with comparable oncological outcome.
引用
收藏
页码:5939 / 5947
页数:9
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