PML: a tumor suppressor essential for neocortical development

被引：5
|
作者：
Schreck, Karisa C. [1 ]
Gaiano, Nicholas [2 ,3 ,4 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Med, Inst Cell Engn, Baltimore, MD 21205 USA
[3] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA
[4] Johns Hopkins Univ, Sch Med, Dept Neurosci & Oncol, Baltimore, MD 21205 USA
来源：
NATURE NEUROSCIENCE | 2009年 / 12卷 / 02期
关键词：
CORTICAL DEVELOPMENT; NERVOUS-SYSTEM; NEUROGENESIS; CELLS; APOPTOSIS; PATHWAY;
D O I：
10.1038/nn0209-108
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Brain development requires precise control of progenitor proliferation and differentiation. PML appears to be a crucial regulator of cortical progenitors, limiting proliferation and promoting the generation of committed neuronal precursors.
引用
收藏
页码：108 / 110
页数：4
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