Association of swine vertnin (VRTN) gene with production traits in Duroc pigs improved using a closed nucleus breeding system

被引：27

作者：

Hirose, Kensuke ^{[1
]}

Mikawa, Satoshi ^{[2
]}

Okumura, Naohiko ^{[3
]}

Noguchi, Go ^{[1
]}

Fukawa, Kazuo ^{[1
]}

Kanaya, Naoe ^{[3
]}

Mikawa, Ayumi ^{[3
]}

Arakawa, Aisaku ^{[2
]}

Ito, Tetsuya ^{[1
]}

Hayashi, Yoichi ^{[1
]}

Tachibana, Fumio ^{[1
]}

Awata, Takashi ^{[2
]}

机构：

[1] ZEN NOH Natl Federat Agr Cooperat Assoc, Cent Res Inst Feed & Livestock, Kamishihoro, Hokkaido 0801406, Japan

[2] ZEN NOH Natl Federat Agr Cooperat Assoc, Natl Inst Agrobiol Sci, Tsukuba, Ibaraki, Japan

[3] ZEN NOH Natl Federat Agr Cooperat Assoc, JATAFF Inst, Tsukuba, Ibaraki, Japan

来源：

ANIMAL SCIENCE JOURNAL | 2013年 / 84卷 / 03期

关键词：

Duroc; polymorphism; vertebral number; vertnin; INTRAMUSCULAR FAT-CONTENT; CARCASS TRAITS; LOCI ANALYSIS; NUMBER; MUSCLE; QTL; IDENTIFICATION; CHROMOSOME-7; RECEPTOR; QUALITY;

D O I：

10.1111/j.1740-0929.2012.01066.x

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Vertnin (VRTN) is involved in the variation of vertebral number in pigs and it is located on Sus scrofa chromosome 7. Vertebral number is related to body size in pigs, and many reports have suggested presence of an association between body length (BL) and meat production traits. Therefore, we analyzed the relationship between the VRTN genotype and the production and body composition traits in purebred Duroc pigs. Intramuscular fat content (IMF) in the Longissimus muscle was significantly associated with the VRTN genotype. The mean IMF of individuals with the wild-type genotype (Wt/Wt) (5.22%) was greater than that of individuals with the Wt/Q (4.99%) and Q/Q genotypes (4.79%). In addition, a best linear unbiased predictor of multiple traits animal model showed that the Wt allele had a positive effect on the IMF breeding value. No associations were observed between the VRTN genotype and other production traits. The VRTN genotype was related to BL. The Q/Q genotype individuals (100.0cm) were longer than individuals with the Wt/Q (99.5cm) and Wt/Wt genotypes (98.9cm). These results suggest that in addition to the maintenance of an appropriate backfat thickness value, VRTN has the potential to act as a genetic marker of IMF.

引用

页码：213 / 221

页数：9

共 28 条

[11]

GROENEVELD E, 1996, REML VCE MULTIVARIAT

[12]

Hazel LN, 1943, GENETICS, V28, P476

[13]

Hicks Chindo, 1998, Animal Science and Technology, V69, P1094

[14] Association of an SNP marker in exon 24 of a class 3 phosphoinositide-3-kinase (PIK3C3) gene with production traits in Duroc pigs [J].

Hirose, Kensuke ;

Takizawa, Tatsuya ;

Fukawa, Kazuo ;

Ito, Tetsuya ;

Ueda, Masayuki ;

Hayashi, Yoichi ;

Tanaka, Kazuaki .

ANIMAL SCIENCE JOURNAL, 2011, 82 (01) :46-51

[15] An insertion/deletion variant of a thymine base in exon 2 of the porcine beta 3-adrenergic receptor gene associated with loin eye muscle area [J].

Hirose, Kensuke ;

Nakamura, Mariko ;

Takizawa, Tatsuya ;

Fukawa, Kazuo ;

Ito, Tetsuya ;

Ueda, Masayuki ;

Sasaki, Takashi ;

Tanaka, Kazuaki .

ANIMAL SCIENCE JOURNAL, 2009, 80 (06) :624-630

[16]

Huff-Lonergan E, 2002, J ANIM SCI, V80, P617

[17]

Mikawa S, 2005, J ANIM SCI, V83, P2247

[18] Fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (NR6A1) [J].

Mikawa, Satoshi ;

Morozumi, Takeya ;

Shimanuki, Shin-Ichi ;

Hayashi, Takeshi ;

Uenishi, Hirohide ;

Domukai, Michiko ;

Okumura, Naohiko ;

Awata, Takashi .

GENOME RESEARCH, 2007, 17 (05) :586-593

[19] Identification of a second gene associated with variation in vertebral number in domestic pigs [J].

Mikawa, Satoshi ;

Sato, Shuji ;

Nii, Masahiro ;

Morozumi, Takeya ;

Yoshioka, Gou ;

Imaeda, Noriaki ;

Yamaguchi, Tsuneko ;

Hayashi, Takeshi ;

Awata, Takashi .

BMC GENETICS, 2011, 12

[20] RECOVERY OF INTER-BLOCK INFORMATION WHEN BLOCK SIZES ARE UNEQUAL [J].

PATTERSON, HD ;

THOMPSON, R .

BIOMETRIKA, 1971, 58 (03) :545-+

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