Antimicrobial peptides activity in the skin

被引：53

作者：

Herman, Anna ^{[1
]}

Herman, Andrzej P. ^{[2
]}

机构：

[1] Warsaw Coll Hlth & Engn, Fac Hlth Sci, Warsaw, Poland

[2] Polish Acad Sci, Kielanowski Inst Anim Physiol & Nutr, Dept Genet Engn, Warsaw, Poland

来源：

SKIN RESEARCH AND TECHNOLOGY | 2019年 / 25卷 / 02期

关键词：

antimicrobial peptide; skin barrier; skin disease; skin immune defense; wound healing; HUMAN BETA-DEFENSIN; INNATE IMMUNE-RESPONSE; ATOPIC-DERMATITIS; HUMAN KERATINOCYTES; IN-VITRO; STAPHYLOCOCCUS-AUREUS; PROTEIN PSORIASIN; PROPIONIBACTERIUM-ACNES; ANTIBACTERIAL PEPTIDES; HUMAN BETA-DEFENSIN-2;

D O I：

10.1111/srt.12626

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

This review presents the current state of knowledge regarding multifunctional role of human skin antimicrobial peptides (AMPs), including (a) protection from microbial infection, (b) improvement of skin barrier homoeostasis, (c) modulation of inflammation responses, and (d) promotion of wound healing. In addition, association of AMPs with skin diseases as well as challenges and future prospects for AMP therapeutics has also been discussed.

引用

页码：111 / 117

页数：7

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