Abnormal Cytology in 2012: Management of Atypical Squamous Cells, Low-grade Intraepithelial Neoplasia, and High-grade Intraepithelial Neoplasia

被引:7
作者
Garrett, Leslie A. [1 ]
McCann, Christopher K. [1 ]
机构
[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Obstet & Gynecol,Div Gynecol Oncol, Boston, MA 02215 USA
关键词
human papillomavirus; cytology; Papanicolaou test; atypical squamous cells; low-grade squamous intraepithelial lesion; high-grade squamous intraepithelial lesion; HUMAN-PAPILLOMAVIRUS TYPES; UNDETERMINED SIGNIFICANCE; CERVICAL CYTOLOGY; FOLLOW-UP; WOMEN; LESIONS; CANCER; RISK; COLPOSCOPY; STRATEGIES;
D O I
10.1097/GRF.0b013e3182833eed
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Cervical cancer and human papillomavirus-related diseases continue to cause significant morbidity and mortality in the United States and worldwide. As we begin to understand the natural course of human papillomavirus infection, and the consequences of both its detection and treatment, changes have been made to our clinical approaches. The purpose of this review is to outline the management guidelines for the management of abnormal cytology. Successful triage of abnormal cytology in 2012 will allow for continued detection of precancerous lesions reducing the incidence of cervical cancer and increasing the detection of early stage disease.
引用
收藏
页码:25 / 34
页数:10
相关论文
共 37 条
[1]   Effective cervical neoplasia detection with a novel optical detection system: A randomized trial [J].
Alvarez, Ronald D. ;
Wright, Thomas C. .
GYNECOLOGIC ONCOLOGY, 2007, 104 (02) :281-289
[2]   Clinical utility of HPV-DNA detection: Triage of minor cervical lesions, follow-up of women treated for high-grade CIN: An update of pooled evidence [J].
Arbyn, M ;
Paraskevaidis, E ;
Martin-Hirsch, P ;
Prendiville, W ;
Dillner, J .
GYNECOLOGIC ONCOLOGY, 2005, 99 (03) :S7-S11
[3]   Virologic versus cytologic triage of women with equivocal pap smears: A meta-analysis of the accuracy to detect high-grade intraepithelial neoplasia [J].
Arbyn, M ;
Buntinx, F ;
Van Ranst, M ;
Paraskevaidis, E ;
Martin-Hirsch, P ;
Dillner, J .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2004, 96 (04) :280-293
[4]   Clinical applications of HPV testing: A summary of meta-analyses [J].
Arbyn, Marc ;
Sasieni, Peter ;
Meijer, Chris J. L. M. ;
Clavel, Christine ;
Koliopoulos, George ;
Dillner, Joakim .
VACCINE, 2006, 24 :78-89
[5]   Papanicolaou test interpretations of "atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion" [J].
Bonvicino, Amanda ;
Hultron, Sonny ;
Fadare, Oluwole .
CANCER CYTOPATHOLOGY, 2007, 111 (06) :477-481
[6]   Human papillomavirus type 16 infections and 2-year absolute risk of cervical precancer in women with equivocal or mild cytologic abnormalities [J].
Castle, PE ;
Solomon, D ;
Schiffman, M ;
Wheeler, CM .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2005, 97 (14) :1066-1071
[7]   The Age-Specific Relationships of Abnormal Cytology and Human Papillomavirus DNA Results to the Risk of Cervical Precancer and Cancer [J].
Castle, Philip E. ;
Fetterman, Barbara ;
Cox, J. Thomas ;
Shaber, Ruth ;
Poitras, Nancy ;
Lorey, Thomas ;
Kinney, Walter .
OBSTETRICS AND GYNECOLOGY, 2010, 116 (01) :76-84
[8]   Bethesda 2001 - Impact on the reporting of gynecologic cytology [J].
Chhieng, DC ;
Roberson, J ;
Gidley, J ;
Eltoum, I .
ACTA CYTOLOGICA, 2004, 48 (03) :355-362
[9]   Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy [J].
Cox, JT ;
Schiffman, M ;
Solomon, D .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2003, 188 (06) :1406-1412
[10]   HPV DNA testing in cervical cancer screening: From evidence to policies [J].
Cox, Tom ;
Cuzick, Jack .
GYNECOLOGIC ONCOLOGY, 2006, 103 (01) :8-11