Subcellular organelle analysis applying confocal laser scanning microscopy to the steroid-producing epithelial ovarian tumor: A technical note

被引：8

作者：

Yasuda, M

Itoh, J

Muramatsu, T

Shinozuka, T

Sasano, H

Tsutsumi, Y

Osamura, RY

机构：

[1] TOKAI UNIV,SCH MED,LABS STRUCT & FUNCT RES,ISEHARA,KANAGAWA 25911,JAPAN

[2] TOKAI UNIV,SCH MED,DEPT OBSTET & GYNECOL,ISEHARA,KANAGAWA 25911,JAPAN

[3] TOHOKU UNIV,SCH MED,DEPT PATHOL,SENDAI,MIYAGI 980,JAPAN

来源：

PATHOLOGY INTERNATIONAL | 1997年 / 47卷 / 05期

关键词：

confocal laser scanning microscopy; epithelial ovarian tumor; steroidogenic stroma;

D O I：

10.1111/j.1440-1827.1997.tb04505.x

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

An epithelial ovarian tumor with steroid production was examined in a 70-year-old postmenopausal female, The stromal cells of this tumor were rather dense and occasionally characterized by luteinization or hyperthecosis, which has been associated with steroidogenesis, Subcellular visualization using confocal laser scanning microscopy (CLSM) successfully led to the identification of 3 beta-hydroxysteroid dehydrogenase (HSD) in both mitochondria-like small particles and endoplasmic reticulum-like linear profiles, and P450-aromatase also in endoplasmic reticulum-like linear profiles, on the three-dimensional images.

引用

页码：336 / 338

页数：3

共 13 条

[1] ULTRACYTOCHEMICAL DEMONSTRATION AND PROBABLE LOCALIZATION OF 3BETA-HYDROXYSTEROID DEHYDROGENASE-ACTIVITY WITH A FERRICYANIDE TECHNIQUE [J].