Dynamics and determinants of Staphylococcus aureus carriage in infancy:: the Generation R Study

被引:73
作者
Lebon, Ankie [2 ,3 ]
Labout, Joost A. M. [2 ,3 ]
Verbrugh, Henri A.
Jaddoe, Vincent W. V. [2 ,3 ,4 ]
Hofman, Albert [2 ,4 ]
van Wamel, Willem
Moll, Henriette A. [2 ,3 ]
van Belkum, Alex [1 ]
机构
[1] Erasmus MC, Dept Med Microbiol & Infect Dis, Unit Res & Dev, NL-3015 CE Rotterdam, Netherlands
[2] Erasmus MC, Generat R Study Grp, NL-3015 CE Rotterdam, Netherlands
[3] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Pediat, Rotterdam, Netherlands
[4] Erasmus MC, Dept Epidemiol, NL-3015 CE Rotterdam, Netherlands
关键词
D O I
10.1128/JCM.00641-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Serial nasal swabs were collected at the ages of 1.5, 6, and 14 months from 443 infants in the Generation R Study. The objective was to study the dynamics and determinants of Staphylococcus aureus nasal carriage in the first year of life. The prevalence of S. aureus carriage decreased in the first year of life, from 52.1% at the age of 1.5 months to 12.9% at 14 months. Persistent carriage, defined as continuous carriage of the same S. aureus strain at the three sampling moments, was rarely detected in early infancy.
引用
收藏
页码:3517 / 3521
页数:5
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