Novel spiro-sesquiterpene from the mushroom Anthracophyllum sp BCC18695

被引：20

作者：

Intaraudom, Chakapong ^{[1
]}

Boonyuen, Nattawut ^{[1
]}

Supothina, Sumalee ^{[1
]}

Tobwor, Punsa ^{[1
]}

Prabpai, Samran ^{[2
]}

Kongsaeree, Palangpon ^{[2
,3
]}

Pittayakhajonwut, Pattama ^{[1
]}

机构：

[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, Klongluang 12120, Pathumthani, Thailand

[2] Mahidol Univ, Dept Chem, Fac Sci, Ctr Excellence Innovat Chem, Bangkok 10400, Thailand

[3] Mahidol Univ, Fac Sci, Ctr Excellence Prot Struct & Funct, Bangkok 10400, Thailand

来源：

PHYTOCHEMISTRY LETTERS | 2013年 / 6卷 / 03期

关键词：

Basidiomycetes; Anthracophyllum; Antimalarial; Sesquiterpenes; Cytotoxicity; DERIVATIVES; RESAZURIN;

D O I：

10.1016/j.phytol.2013.04.006

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A novel spiro-sesquiterpene, anthracophyllic acid (1), and a new aristolane sesquiterpene, anthracophyllone (2), were isolated from the mushroom Anthracophyllum sp. BCC18695, together with seven known compounds including aurisins A (3), G (4), K (5), nambinones A, C, axinysones A, and B. The relative configuration of 1 and the hitherto unknown absolute stereochemistry of 3 were determined based on X-ray spectroscopic data. Biological activities including antimalarial activity against Plasmodium falciparum K1 strain, antibacterial property against Bacillus cereus, and cytotoxicity against MCF-7, KB, NCI-H187, and Vero cells of the isolated compounds were also evaluated (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

引用

页码：345 / 349

页数：5

共 16 条

[1] SIR97:: a new tool for crystal structure determination and refinement [J].

Altomare, A ;

Burla, MC ;

Camalli, M ;

Cascarano, GL ;

Giacovazzo, C ;

Guagliardi, A ;

Moliterni, AGG ;

Polidori, G ;

Spagna, R .

JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1999, 32 :115-119

[2] REACTIONS OF NINHYDRIN WITH ACTIVATED ANILINES - FORMATION OF INDOLE-DERIVATIVES [J].

BLACK, DS ;

BOWYER, MC ;

CONDIE, GC ;

CRAIG, DC ;

KUMAR, N .

TETRAHEDRON, 1994, 50 (37) :10983-10994

[3]

Boehlendorf B., 2004, Brit. UK Pat. Appl., Patent No. [GB 2396349 A 20040623, 2396349]

[4] Improved green fluorescent protein reporter gene-based microplate screening for antituberculosis compounds by utilizing an acetamidase promoter [J].

Changsen, C ;

Franzblau, SG ;

Palittapongarnpim, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (12) :3682-3687

[5] Terpenoids from Russula lepida and R. amarissima (Basidiomycota, Russulaceae) [J].

Clericuzio, Marco ;

Cassino, Claudio ;

Corana, Federica ;

Vidari, Giovanni .

PHYTOCHEMISTRY, 2012, 84 :154-159

[6] QUANTITATIVE ASSESSMENT OF ANTI-MALARIAL ACTIVITY INVITRO BY A SEMIAUTOMATED MICRODILUTION TECHNIQUE [J].

DESJARDINS, RE ;

CANFIELD, CJ ;

HAYNES, JD ;

CHULAY, JD .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1979, 16 (06) :710-718

[7]

Hall T., 2006, BIOEDIT

[8]

JAGERS E, 1987, Z NATURFORSCH B, V42, P1354

[9] Cytotoxic sesquiterpenes from luminescent mushroom Neonothopanus nambi [J].

Kanokmedhakul, Somdej ;

Lekphrom, Ratsami ;

Kanokmedhakul, Kwanjai ;

Hahnvajanawong, Chariya ;

Bua-art, Sureeporn ;

Saksirirat, Weerasak ;

Prabpai, Samran ;

Kongsaeree, Palangpon .

TETRAHEDRON, 2012, 68 (39) :8261-8266

[10] Natural terphenyls: Developments since 1877 [J].

Liu, Ji-Kai .

CHEMICAL REVIEWS, 2006, 106 (06) :2209-2223

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