dGTP-Templated Luminescent Gold Nanocluster-Based Composite Nanoparticles for Cancer Theranostics

被引：10
作者：
Chatterjee, Bandhan [1 ]
Ghoshal, Archita [2 ]
Chattopadhyay, Arun [3 ]
Ghosh, Siddhartha Sankar [2 ]
机构：
[1] Indian Inst Technol Guwahati, Ctr Nanotechnol, Gauhati 781039, Assam, India
[2] Indian Inst Technol Guwahati, Dept Biosci & Bioengn, Gauhati 781039, Assam, India
[3] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, Assam, India
来源：
ACS BIOMATERIALS SCIENCE & ENGINEERING | 2018年 / 4卷 / 03期
关键词：
Au nanoclusters; cisplatin; composite NPs; apoptosis; theranostic; DRUG-DELIVERY; CISPLATIN; NANOMATERIALS; THERAPY; GREEN; CELLS;
D O I：
10.1021/acsbiomaterials.7b00980
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
dGTP-templated facile synthesis of luminescent gold nanoclusters (Au NCs) in the presence of cisplatin following PEG coating developed spherical composite NPs. The composite NPs delivered cisplatin efficiently into HeLa cells to induce apoptosis-mediated cell death, and simultaneously bioimaged the cellular uptake.
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页码：1005 / 1012
页数：15
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