Partly adaptive elastic net and its application to microarray classification

被引:25
作者
Li, Juntao [1 ]
Jia, Yingmin [2 ]
Zhao, Zhihua [1 ]
机构
[1] Henan Normal Univ, Coll Math & Informat Sci, Xingxiang 453007, Peoples R China
[2] Beihang Univ BUAA, Res Div 7, Beijing 100191, Peoples R China
关键词
Partly adaptive elastic net; Microarray classification; Gene selection; Pathwise coordinate descent; FEATURE-SELECTION; MODEL SELECTION; REGRESSION; CANCER; REGULARIZATION;
D O I
10.1007/s00521-012-0885-6
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
This paper presents a new extension of the elastic net for simultaneous gene selection and microarray classification. By introducing the proper data-driven weights to the penalty terms, the partly adaptive elastic net is proposed, which can encourage an adaptive grouping effect and reduce the influence of the wrong initial estimation. A fast-solving algorithm is also developed in the line of pathwise coordinate descent. Experiments performed on the two cancer data sets are provided to verify the obtained results.
引用
收藏
页码:1193 / 1200
页数:8
相关论文
共 26 条
[1]  
[Anonymous], 2006, Journal of the Royal Statistical Society, Series B
[2]  
Cawley GC, 2007, J MACH LEARN RES, V8, P841
[3]   Gene selection in cancer classification using sparse logistic regression with Bayesian regularization [J].
Cawley, Gavin C. ;
Talbot, Nicola L. C. .
BIOINFORMATICS, 2006, 22 (19) :2348-2355
[4]   Clustering cancer gene expression data: a comparative study [J].
de Souto, Marcilio C. P. ;
Costa, Ivan G. ;
de Araujo, Daniel S. A. ;
Ludermir, Teresa B. ;
Schliep, Alexander .
BMC BIOINFORMATICS, 2008, 9 (1)
[5]   Comparison of discrimination methods for the classification of tumors using gene expression data [J].
Dudoit, S ;
Fridlyand, J ;
Speed, TP .
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 2002, 97 (457) :77-87
[6]   Least angle regression - Rejoinder [J].
Efron, B ;
Hastie, T ;
Johnstone, I ;
Tibshirani, R .
ANNALS OF STATISTICS, 2004, 32 (02) :494-499
[7]  
Friedman J., 2008, TECHNICAL REPORT
[8]   PATHWISE COORDINATE OPTIMIZATION [J].
Friedman, Jerome ;
Hastie, Trevor ;
Hoefling, Holger ;
Tibshirani, Robert .
ANNALS OF APPLIED STATISTICS, 2007, 1 (02) :302-332
[9]   Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring [J].
Golub, TR ;
Slonim, DK ;
Tamayo, P ;
Huard, C ;
Gaasenbeek, M ;
Mesirov, JP ;
Coller, H ;
Loh, ML ;
Downing, JR ;
Caligiuri, MA ;
Bloomfield, CD ;
Lander, ES .
SCIENCE, 1999, 286 (5439) :531-537
[10]   Gene selection for cancer classification using support vector machines [J].
Guyon, I ;
Weston, J ;
Barnhill, S ;
Vapnik, V .
MACHINE LEARNING, 2002, 46 (1-3) :389-422