Small bowel capsule endoscopy for management of Crohn's disease: A retrospective tertiary care centre experience

被引：41

作者：

Dussault, Catherine ^{[1
]}

Gower-Rousseau, Corinne ^{[2
]}

Salleron, Julia ^{[3
]}

Vernier-Massouille, Gwenola ^{[1
]}

Branche, Julien ^{[1
]}

Colombel, Jean-Frederic ^{[1
]}

Maunoury, Vincent ^{[1
]}

机构：

[1] Univ Nord France, Lille Univ & Hosp, Hop Huriez, Gastroenterol Unit, Lille, France

[2] Univ Nord France, Lille Univ & Hosp, Epidemiol Unit, EA 2694, Lille, France

[3] Univ Lille Nord France, Lille Univ & Hosp, Dept Biostat, EA2694, F-59000 Lille, France

来源：

DIGESTIVE AND LIVER DISEASE | 2013年 / 45卷 / 07期

关键词：

Crohn's disease; Videocapsule endoscopy; Therapeutic management; CONSENSUS; DIAGNOSIS; INDEX;

D O I：

10.1016/j.dld.2012.11.004

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: The role of small bowel capsule endoscopy in the management of established Crohn's disease is uncertain. Methods: A retrospective study of small bowel capsule endoscopy tests performed in a referral centre from 2008 to 2011; 77 tests were performed in patients with known Crohn's disease. Six patients were excluded due to capsule test retention. Patients were classified into 4 indication groups: unexplained anaemia (G1, n = 6); discrepancy between clinical symptoms and morphology (G2, n = 25), full assessment of Crohn's disease location (G3, n = 37) and evaluation of mucosal healing (G4, n = 3). Results: Twenty-seven (38%) patients had no lesions, 32 (45%) moderate and 12 (17%) severe lesions. Endoscopic lesions were found in 4/6 (67%) G1 patients, 11/25 (44%) G2 and 28/37 (76%) G3 (p < 0.03). Three months after endoscopy was performed, 38/71 patients experienced a change in their treatment that was significantly associated with the severity of endoscopic lesions and with test indications; in 60%, 20% and 58% of patients from G1, G2 and G3, respectively (p < 0.01). Conclusion: Small bowel capsule endoscopy resulted in management changes in the majority of patients with established Crohn's disease. (c) 2012 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

引用

页码：558 / 561

页数：4

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