Two new lignans from the stems of Schisandra bicolor

被引：8

作者：

Huang, Ri-Ming ^{[1
]}

Huang, Hui-Juan ^{[2
]}

Zhang, Nen-Ling ^{[1
]}

Zhu, Yue-Hui ^{[1
]}

Jiang, Xiao-Fei ^{[1
,3
]}

Su, Zhi-Wei ^{[1
]}

Yang, Jian-Xiang ^{[1
]}

Xu, Zhi-Fang ^{[1
]}

Li, Chuan-Rong ^{[4
]}

Qiu, Samuel X. ^{[1
]}

机构：

[1] Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, S China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China

[2] S China Normal Univ, Guangdong Prov Key Lab Biotechnol Plant Dev, Guangzhou 510631, Guangdong, Peoples R China

[3] Chongqing Three Gorges Univ, Coll Chem & Environm Engn, Chongqing 404000, Peoples R China

[4] Chinese Acad Sci, S China Sea Inst Oceanol, Lab NMR Anal & Measurement, Guangzhou 510301, Guangdong, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2012年 / 14卷 / 12期

基金：

中国国家自然科学基金;

关键词：

Schisandra bicolor; lignans; zuihonins E and F; TRITERPENOIDS; CHINENSIS;

D O I：

10.1080/10286020.2012.725394

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new lignans, named zuihonins E (1) and F (2), were isolated from the stems of Schisandra bicolor Cheng var. tuberculata Law. The structures of the new lignans were elucidated on the basis of extensive spectroscopic analysis, including 1D, 2D NMR, and MS experiments, and their absolute stereochemistry was determined by circular dichroism spectrum. Compounds 1 and 2 did not inhibit the growth of hepatoma carcinoma cell (HepG2), lung carcinoma cell (A549), and human breast carcinoma (MCF-7) cell lines.

引用

页码：1116 / 1121

页数：6

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