Ni-catalyzed two-component reductive dicarbofunctionalization of alkenes via radical cyclization

被引：77

作者：

Kuang, Yulong ^{[1
]}

Wang, Xuefeng ^{[1
]}

Anthony, David ^{[1
]}

Diao, Tianning ^{[1
]}

机构：

[1] NYU, 100 Washington Sq E, New York, NY 10003 USA

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 20期

基金：

美国国家科学基金会;

关键词：

UNACTIVATED ALKYL-HALIDES; CROSS-COUPLING REACTIONS; CARBONYL-COMPOUNDS; RING-CLOSURE; ARYL IODIDES; ELECTROPHILES; DIARYLATION; BROMIDES; OLEFINS; ARYLATION;

D O I：

10.1039/c8cc00358k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A reductive dicarbofunctionalization reaction of alkenes has been developed and applied to the preparation of substituted carbo- and heterocycles. The reaction conditions avoid the use of air-sensitive organometallic reagents, and are compatible with a broad range of bromo-electrophiles and a wide variety of substituents to give cyclic products in excellent yields.

引用

页码：2558 / 2561

页数：4

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