Research Progress on Near Infrared II Technology for in Vivo Imaging

被引：14
作者：
Luo Xingrui [1 ,2 ,3 ]
Chen Minwen [4 ]
Yang Qinglai [1 ,2 ,3 ,4 ]
机构：
[1] Univ South China, Canc Res Inst Med Coll, Hengyang 421001, Peoples R China
[2] Univ South China, Inst Pharm & Pharmacol, Hengyang 421001, Peoples R China
[3] Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Inst Mol Med, Shanghai 200127, Peoples R China
[4] Tsinghua Univ Shenzhen, Res Inst, Shenzhen 518057, Peoples R China
来源：
ACTA CHIMICA SINICA | 2020年 / 78卷 / 05期
基金：
中国国家自然科学基金;
关键词：
near infrared II; fluorescent probe; in vivo imaging; clinical transformation; CONFOCAL MICROSCOPY; SPATIAL-RESOLUTION; FLUORESCENT-PROBE; CARBON NANOTUBES; FLUOROPHORES; WINDOW; BRAIN; CELL; SURGERY; DESIGN;
D O I：
10.6023/A20020045
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Near infrared II (NIR., 1000 similar to 1700 nm) biological imaging, as a new developing optical imaging technology in recent years, has longer fluorescence wavelength compared with the traditional near infrared I (NIR I, 750 similar to 900 nm) and visible light (Vis, 400 similar to 750 nm) imaging. Due to the longer emission wavelength, weaker interference by light scattering and tissue autofluorescence, result in higher temporal and spatial resolution with deeper tissue penetration. This technology is more suitable for in vivo imaging in situ. In this review, we mainly introduced research progress on NIR II instrument technology for in vivo imaging, and summarized its major features. Finally, we provided a prospect that the development of chemical materials, optoelectronic instruments, and multi-modal technologies can promote NIR II technology innovation, which is expected to be widely and deeply applied in clinical transformation.
引用
收藏
页码：373 / 381
页数：9
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