A New Saponin from Tea Seed Pomace (Camellia oleifera Abel) and Its Protective Effect on PC12 Cells

被引：45
作者：
Zhang, Xin-Fu [2 ,3 ,4 ]
Han, Ying-Ying [2 ,3 ]
Bao, Guan-Hu [2 ,3 ]
Ling, Tie-Jun [2 ,3 ]
Zhang, Liang [2 ,3 ]
Gao, Li-Ping [1 ]
Xia, Tao [2 ,3 ]
机构：
[1] Anhui Agr Univ, Sch Life Sci, Hefei 230036, Peoples R China
[2] Anhui Agr Univ, Key Lab Tea Biochem & Biotechnol, Minist Educ, Hefei 230036, Peoples R China
[3] Anhui Agr Univ, Minist Agr, Hefei 230036, Peoples R China
[4] Qingdao Agr Univ, Coll Hort, Qingdao 266109, Peoples R China
来源：
MOLECULES | 2012年 / 17卷 / 10期
关键词：
Camellia oleifera; tea seed pomace; triterpenoid; saponin; PC12; cell; TRITERPENE SAPONINS; BIOACTIVE SAPONINS; SINENSIS; GLYCOSIDES; SASANQUASAPONIN; OLIGOGLYCOSIDES; PLANT; CONSTITUENTS; INJURY;
D O I：
10.3390/molecules171011721
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new triterpenoid saponin, oleiferasaponin A(1), was isolated from tea seed pomace (Camellia oleifera Abel). The structure of oleiferasaponin A(1) was elucidated on the basis of chemical and physicochemical evidence and was found to be 22-O-cis-2-hexenoyl-A(1)-barrigenol 3-O-[beta-D-galactopyranosyl(1 -> 2)] [beta-D-glucopyranosyl(1 -> 2)-alpha-L-arabinopyranosyl(1 -> 3)]-beta-D-glucopyranosiduronic acid. PC12 cells injured with H2O2 were used as the model to test the protective effects of oleiferasaponin A(1). The results indicated that oleiferasaponin A(1) can potentially prevent the H2O2-induced cell death of PC12 cells.
引用
收藏
页码：11721 / 11728
页数：8
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