Control of Oxygenation During Mechanical Ventilation in the Premature Infant

被引:19
作者
Bancalari, Eduardo [1 ]
Claure, Nelson [1 ]
机构
[1] Univ Miami, Miller Sch Med, Div Neonatol, Dept Pediat, Miami, FL 33136 USA
关键词
Oxygen saturation targets; Hypoxemia; Hyperoxemia; Supplemental oxygen; Premature infants; EXTREMELY PRETERM INFANTS; PULSE OXIMETER SATURATION; BIRTH-WEIGHT INFANTS; CLOSED-LOOP CONTROL; INSPIRED OXYGEN; ARTERIAL OXYGEN; BRONCHOPULMONARY DYSPLASIA; EPISODES; HYPOXEMIA; TENSION;
D O I
10.1016/j.clp.2012.06.013
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Maintenance of oxygen saturation targets is a demanding and tedious task because of the frequency with which oxygenation changes, especially in small infants receiving prolonged respiratory support. It is clear that the achievement of oxygenation targets can be improved by a higher nurse-to-patient ratio and by intense staff training. Automated control systems can also improve target maintenance, and this is achieved mainly by reducing exposure to hyperoxemia. The long-term benefits and safety of this strategy are yet to be determined in clinical trials.
引用
收藏
页码:563 / +
页数:11
相关论文
共 34 条
[1]   Oxygen-saturation targets and outcomes in extremely preterm infants [J].
Askie, LM ;
Henderson-Smart, DJ ;
Irwig, L ;
Simpson, JM .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (10) :959-967
[2]   NEW TECHNIQUE FOR SERVO-CONTROL OF ARTERIAL OXYGEN-TENSION IN PRETERM INFANTS [J].
BEDDIS, IR ;
COLLINS, P ;
LEVY, NM ;
GODFREY, S ;
SILVERMAN, M .
ARCHIVES OF DISEASE IN CHILDHOOD, 1979, 54 (04) :278-280
[3]   ADAPTIVE-CONTROL OF INSPIRED OXYGEN DELIVERY TO THE NEONATE [J].
BHUTANI, VK ;
TAUBE, JC ;
ANTUNES, MJ ;
DELIVORIAPAPADOPOULOS, M .
PEDIATRIC PULMONOLOGY, 1992, 14 (02) :110-117
[4]   MECHANISMS FOR EPISODES OF HYPOXEMIA IN PRETERM INFANTS UNDERGOING MECHANICAL VENTILATION [J].
BOLIVAR, JM ;
GERHARDT, T ;
GONZALEZ, A ;
HUMMLER, H ;
CLAURE, N ;
EVERETT, R ;
BANCALARI, E .
JOURNAL OF PEDIATRICS, 1995, 127 (05) :767-773
[5]  
CARLO WA, 1986, PEDIATRICS, V78, P139
[6]   Target Ranges of Oxygen Saturation in Extremely Preterm Infants. [J].
Carlo, Waldemar A. ;
Finer, Neil N. ;
Walsh, Michele C. ;
Rich, Wade ;
Gantz, Marie G. ;
Laptook, Abbot R. ;
Yoder, Bradley A. ;
Faix, Roger G. ;
Das, Abhik ;
Poole, W. Kenneth ;
Schibler, Kurt ;
Newman, Nancy S. ;
Ambalavanan, Namasivayam ;
Frantz, Ivan D., III ;
Piazza, Anthony J. ;
Sanchez, Pablo J. ;
Morris, Brenda H. ;
Laroia, Nirupama ;
Phelps, Dale L. ;
Poindexter, Brenda B. ;
Cotten, C. Michael ;
Van Meurs, Krisa P. ;
Duara, Shahnaz ;
Narendran, Vivek ;
Sood, Beena G. ;
O'Shea, T. Michael ;
Bell, Edward F. ;
Ehrenkranz, Richard A. ;
Watterberg, Kristi L. ;
Higgins, Rosemary D. ;
Jobe, A. H. ;
Caplan, M. S. ;
Oh, W. ;
Hensman, A. M. ;
Gingras, D. ;
Barnett, S. ;
Lillie, S. ;
Francis, K. ;
Andrews, D. ;
Angela, K. ;
Fanaroff, A. A. ;
Siner, B. S. ;
Zadell, A. ;
DiFiore, J. ;
Donovan, E. F. ;
Bridges, K. ;
Alexander, B. ;
Grisby, C. ;
Mersmann, M. W. ;
Mincey, H. L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (21) :1959-1969
[7]   Pulse oxygen saturation levels and arterial oxygen tension values in newborns receiving oxygen therapy in the neonatal intensive care unit: Is 85% to 93% an acceptable range? [J].
Castillo, Armando ;
Sola, Augusto ;
Baquero, Hernando ;
Neira, Freddy ;
Alvis, Ramiro ;
Deulofeut, Richard ;
Critz, Ann .
PEDIATRICS, 2008, 121 (05) :882-889
[8]   Closed-loop controlled inspired oxygen concentration for mechanically ventilated very low birth weight infants with frequent episodes of hypoxemia [J].
Claure, N ;
Gerhardt, T ;
Everett, R ;
Musante, G ;
Herrera, C ;
Bancalari, E .
PEDIATRICS, 2001, 107 (05) :1120-1124
[9]   Multicenter Crossover Study of Automated Control of Inspired Oxygen in Ventilated Preterm Infants [J].
Claure, Nelson ;
Bancalari, Eduardo ;
D'Ugard, Carmen ;
Nelin, Leif ;
Stein, Melanie ;
Ramanathan, Rangasamy ;
Hernandez, Richard ;
Donn, Steven M. ;
Becker, Michael ;
Bachman, Thomas .
PEDIATRICS, 2011, 127 (01) :E76-E83
[10]   Automated Adjustment of Inspired Oxygen in Preterm Infants with Frequent Fluctuations in Oxygenation: A Pilot Clinical Trial [J].
Claure, Nelson ;
D'Ugard, Carmen ;
Bancalari, Eduardo .
JOURNAL OF PEDIATRICS, 2009, 155 (05) :640-U75