On the role of aromatic-sugar interactions in the molecular recognition of carbohydrates:: A 3D view by using NMR

被引：23

作者：

Dolores Diaz, M. ^{[1
]}

del Carmen Fernandez-Alonso, Maria ^{[1
]}

Cuevas, Gabriel ^{[2
]}

Javier Canada, F. ^{[1
]}

Jimenez-Barbero, Jesus ^{[1
]}

机构：

[1] CSIC, Biol Res Ctr, E-28040 Madrid, Spain

[2] Univ Nacl Autonoma Mexico, Inst Chem, Mexico City 04510, DF, Mexico

来源：

PURE AND APPLIED CHEMISTRY | 2008年 / 80卷 / 08期

关键词：

NMR; molecular recognition; interactions; carbohydrates; aromatics;

D O I：

10.1351/pac200880081827

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This revision describes an up-to-date review of our efforts to investigate the interaction of carbohydrates with aromatic moieties at different levels of complexity. Protein-Sugar interactions have been studied using NMR experiments oil a variety of hevein/chitooligosaccharide systems. In addition, NMR and computational methods have also been used to evaluate the interaction of simple aromatic entities with simple monosaccharides. In between, the stacking features of aromatic-containing -glycomolecules have also been described by using an analogous experimental-theoretical approach.

引用

页码：1827 / 1835

页数：9

共 58 条

[1] NMR and modeling studies of protein-carbohydrate interactions:: Synthesis, three-dimensional structure, and recognition properties of a minimum hevein domain with binding affinity for chitooligosaccharides [J].