A Randomized Trial on Health-Related Patient Satisfaction Level with High-Efficiency Online Hemodiafiltration versus High-Flux Dialysis

被引:35
作者
Karkar, Ayman [1 ]
Abdelrahman, Mohammed [1 ]
Locatelli, Francesco [2 ]
机构
[1] Dammam Med Complex, Kanoo Kidney Ctr, Dept Nephrol, Dammam 31463, Saudi Arabia
[2] Alessandro Manzoni Hosp, Dept Nephrol & Dialysis, Lecce, Italy
关键词
Dialysis adequacy; Hemodialysis; High-flux; Health-related satisfaction; Quality of life; Online hemodiafiltration; Chronic kidney disease; Chronic renal insufficiency; QUALITY-OF-LIFE; PATIENTS RECEIVING HEMODIAFILTRATION; CHRONIC-HEMODIALYSIS PATIENTS; ALL-CAUSE MORTALITY; CONVECTIVE-TRANSPORT; CROSS-OVER; INFLAMMATION; MODALITY; REMOVAL; RISK;
D O I
10.1159/000381255
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background/Aim: Our aim was to investigate the effect of on-line HDF versus high-flux (HF) hemodialysis (HD) on a patient's health-related satisfaction level. Methods: Overall, 72 patients, on regular low-flux HD for 51 +/- 26 month mean age of 54 +/- 12 years, were randomized to HF (group 1, n = 36) and to HDF (group 2, n = 36) and followed up for 24 months. Assessment was based on the patient's satisfaction level using modified questionnaires of the validated Kidney Disease Quality of Life-Short Form (KDQOL-SF) version 1.3. Results: The HDF group achieved a higher satisfaction level than the HF group (p < 0.0001) with less cramps (3 +/- 5 vs. 55 +/- 8), itching (9 +/- 10 vs. 48 +/- 10), joint pain and stiffness (24 +/- 10 vs. 83 +/- 8), and improvement in general mood (94 +/- 9 vs. 28 +/- 16), sexual performance (57 +/- 10 vs. 5 +/- 5), and social activity (82 +/- 9 vs. 15 +/- 8). Conclusion: High-efficiency postdilution on-line HDF versus high-flux HD significantly improved patients' satisfaction and quality of life, including social, physical, and professional activities. (C) 2015 S. Karger AG, Basel
引用
收藏
页码:84 / 91
页数:8
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