Factor V-Leiden and thrombophilia

被引：34
作者：
Kalafatis, M [1 ]
Mann, KG [1 ]
机构：
[1] UNIV VERMONT, COLL MED, DEPT BIOCHEM, BURLINGTON, VT 05405 USA
来源：
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY | 1997年 / 17卷 / 04期
关键词：
activated protein C; venous thrombosis; activated protein C resistance; factor V-Leiden; thrombophilla;
D O I：
10.1161/01.ATV.17.4.620
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：620 / 627
页数：8
相关论文
共 87 条
[1]   INCREASED RISK OF VENOUS THROMBOSIS IN CARRIERS OF HEREDITARY PROTEIN-C DEFICIENCY DEFECT [J].
ALLAART, CF ;
POORT, SR ;
ROSENDAAL, FR ;
REITSMA, PH ;
BERTINA, RM ;
BRIET, E .
LANCET, 1993, 341 (8838) :134-138
[2]   Molecular mechanisms of activated protein C resistance - Properties of factor V isolated from an individual with homozygosity for the Arg(506) to Gin mutation in the factor V gene [J].
Aparicio, C ;
Dahlback, B .
BIOCHEMICAL JOURNAL, 1996, 313 :467-472
[3]   An antifibrinolytic mechanism describing the prothrombotic effect associated with factor V-Leiden [J].
Bajzar, L ;
Kalafatis, M ;
Simioni, P ;
Tracy, PB .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (38) :22949-22952
[4]   PURIFICATION AND CHARACTERIZATION OF TAFI, A THROMBIN-ACTIVABLE FIBRINOLYSIS INHIBITOR [J].
BAJZAR, L ;
MANUEL, R ;
NESHEIM, ME .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (24) :14477-14484
[5]  
BAZJAR L, 1996, BLOOD, V88, P2093
[6]   THE STRUCTURE AND EVOLUTION OF A 461 AMINO-ACID HUMAN PROTEIN-C PRECURSOR AND ITS MESSENGER-RNA, BASED UPON THE DNA-SEQUENCE OF CLONED HUMAN-LIVER CDNAS [J].
BECKMANN, RJ ;
SCHMIDT, RJ ;
SANTERRE, RF ;
PLUTZKY, J ;
CRABTREE, GR ;
LONG, GL .
NUCLEIC ACIDS RESEARCH, 1985, 13 (14) :5233-5247
[7]   MUTATION IN BLOOD-COAGULATION FACTOR-V ASSOCIATED WITH RESISTANCE TO ACTIVATED PROTEIN-C [J].
BERTINA, RM ;
KOELEMAN, BPC ;
KOSTER, T ;
ROSENDAAL, FR ;
DIRVEN, RJ ;
DERONDE, H ;
VANDERVELDEN, PA ;
REITSMA, PH .
NATURE, 1994, 369 (6475) :64-67
[8]  
BOVILL EG, 1989, BLOOD, V73, P712
[9]   PROTEIN-CVERMONT - SYMPTOMATIC TYPE-II PROTEIN-C DEFICIENCY ASSOCIATED WITH 2 GLA DOMAIN MUTATIONS [J].
BOVILL, EG ;
TOMCZAK, JA ;
GRANT, B ;
BHUSHAN, F ;
PILLEMER, E ;
RAINVILLE, IR ;
LONG, GL .
BLOOD, 1992, 79 (06) :1456-1465
[10]   STRUCTURE OF THE GENE FOR HUMAN COAGULATION FACTOR-V [J].
CRIPE, LD ;
MOORE, KD ;
KANE, WH .
BIOCHEMISTRY, 1992, 31 (15) :3777-3785
123456789