Functional outcome after traumatic cervical spinal cord injury is superior in adolescents compared to adults

被引：6

作者：

Geuther, Martina ^{[1
]}

Grassner, Lukas ^{[1
,2
,3
,4
]}

Mach, Orpheus ^{[1
]}

Klein, Barbara ^{[3
,4
]}

Hoegel, Florian ^{[1
,5
,6
]}

Voth, Maika ^{[7
]}

Buehren, Volker ^{[1
]}

Maier, Doris ^{[1
]}

Abel, Rainer ^{[8
]}

Weidner, Norbert ^{[9
]}

Rupp, Ruediger ^{[9
]}

Fuerstenberg, Carl Hans ^{[10
]}

Schneidmueller, Dorien ^{[11
]}

机构：

[1] Trauma Ctr, Ctr Spinal Cord Injuries, Prof Kuntscher Str 8, D-82418 Murnau, Germany

[2] Trauma Ctr, Dept Neurosurg, Prof Kuntscher Str 8, D-82418 Murnau, Germany

[3] Paracelsus Med Univ, Inst Mol Regenerat Med, Strubergasse 22, A-5020 Salzburg, Austria

[4] Paracelsus Med Univ, Spinal Cord Injury & Tissue Regenerat Ctr, Strubergasse 22, A-5020 Salzburg, Austria

[5] Trauma Ctr Murnau, Inst Biomech, Murnau, Germany

[6] Paracelsus Med Univ, Strubergasse 22, A-5020 Salzburg, Austria

[7] Goethe Univ Frankfurt, Dept Trauma Hand & Reconstruct Surg, Theodor Stern Kai 7, D-60596 Frankfurt, Germany

[8] Klin Hohe Warte, Spinal Cord Injury Ctr, Hohe Warte 8, D-95445 Bayreuth, Germany

[9] Heidelberg Univ Hosp, Spinal Cord Injury Ctr, Schlierbacher Landstr 200a, D-69118 Heidelberg, Germany

[10] SRH Klinikum Karlsbad Langensteinbach, Spinal Cord Injury Ctr, Guttmannstr 1, D-76307 Karlsbad, Germany

[11] Trauma Ctr, Dept Pediat Traumatol, Prof Kuntscher Str 8, D-82418 Murnau, Germany

[12] European Multictr Study Human Spinal Cord Injury, Zurich, Switzerland

来源：

EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY | 2019年 / 23卷 / 02期

关键词：

Spinal cord injury; Cervical spine; Outcome; Children; Adolescents; INDEPENDENCE MEASURE; CHILDREN;

D O I：

10.1016/j.ejpn.2018.12.001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: Determining differences in neurological and functional outcome between adolescents and adults after acute traumatic spinal cord injury (SCI). Design: Retrospective, multi-center case-control study. Methods: 100 cases of patients under 18 years at accident with acute traumatic cervical SCI admitted to SCI centers participating in the European Multi-center study about SCI (EMSCI) between January 2005 and April 2016 were reviewed. According to their age at accident, age 13 to 17, patients were selected for the adolescent group. After applying in- and exclusion criteria 32 adolescents were included. Each adolescent patient was matched with two adult SCI patients for analysis. Outcome measures: ASIA Impairment scale (AIS) grade, neurological, sensory, motor level, total motor score, and Spinal Cord Independence Measure (SCIM III) total score. Results: Mean AIS conversion, neurological, motor and sensory levels as well as total motor score showed no significantly statistical difference in adolescents compared to the adult control group after follow up of 6 months. Significantly higher final SCIM scores (p < 0.05) in the adolescent group compared to adults as well as a strong trend for a higher gain in SCIM score (p < 0.061) between first and last follow up was found. Conclusions: Neurological outcome after traumatic cervical SCI is not superior in adolescents compared to adults in this cohort. Significantly higher SCIM scores indicate more functional gain for the adolescent patients after traumatic cervical SCI. Juvenile age appears to be an independent predictor for a better functional outcome. (C) 2018 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：248 / 253

页数：6

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